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UnknownImpact of headache frequency and preventive medication failure on quality of life, functioning, and costs among individuals with migraine across several European countries: need for effective preventive treatment.
Not available
S-EPMC10464178 | biostudies-literature
ProteomicsTemporally-resolved proteomic profiling of mouse pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is characterized by progressive matrix deposition and fibrosis, which can enhance tumor progression and spread. Here, we undertook an unbiased temporal assessment of the matrix proteome (matrisome) of the highly-metastatic KPC and poorly-metastatic KPflC mouse...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-10 | PXD045830 | Pride
Cancer Pancreas Extracellular matrix 
ProteomicsProteomic analysis Carcinoma associated fibroblasts (CAFs) following genetic manipulation of NID2 expression
Proteomic anlaysis was performed on CAF GFP-1 KRAB, CAF B500 NID2 KRAB and CAF C500 NID2 KRAB cell lines
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD050045 | Pride
Carcinoma associated fibroblasts Nid2 
MetabolomicsDietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-...

2023-01-11 | MTBLS5959 | MetaboLights
GenomicsGoT2D: Genetics of Type 2 Diabetes, a study of the the genetic architecture of type 2 diabetes using low pass whole genome sequencing and high density SNP genotyping in 2,657 individuals.
The Genetics of Type 2 Diabetes Consortium (GoT2D) is a collaboration between the University of Michigan, the Broad Institute and the Wellcome Trust Centre for Human Genetics. The overall aim is to extend upon recent efforts, such as genome-wide association studies (GWAS) and large scale meta-analys...
EGAS00001001459 | EGA
UnknownFamily-GWAS reveals effects of environment and mating on genetic associations.
Not available
S-EPMC12633112 | biostudies-literature
UnknownTales of diversity: Genomic and morphological characteristics of forty-six Arthrobacter phages.
Not available
S-EPMC5513430 | biostudies-literature
UnknownWhole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.
Not available
S-EPMC6904857 | biostudies-literature
UnknownInherited causes of clonal haematopoiesis in 97,691 whole genomes.
Not available
S-EPMC7944936 | biostudies-literature
UnknownEffects of Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use in Participants With Type 2 Diabetes and Chronic Kidney Disease: A FLOW Trial Prespecified Secondary Analysis.
Not available
S-EPMC12583412 | biostudies-literature
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