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ProteomicsSIRT_mutant interactome - Comparative interactomes of SIRT6 and SIRTimplication of functional links to aging
In the present study, we identified SIRT6 (S56Y)- and SIRT7 (H187Y)-interacting proteins, and compared their interactomes to investigate functional links.
Extra primary submitter: Namgyu Lee, Department of Life Sciences, Pohang University of ...
ORGANISM(S): Homo sapiens (Human) 
2014-04-28 | PXD000850 | Pride
Sirt7 Mutant Sirt6 
ProteomicsREST-interactome - Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation
Namgyu Lee has participated in the experimental part of this project and she is a co-first author of the under-going manuscript. RE-1 silencing transcription factor (REST) is a transcriptional repressor with a role in regulating gene expression through binding to repressor element 1. We identified R...
ORGANISM(S): Homo sapiens (Human) 
2018-10-25 | PXD003210 | Pride
Interaction profiling Cell biology Proteomics Transcription factor Lc-ms/ms 
ProteomicsSIRT6 and SIRT7 binding proteome
To find the SIRT6 and SIRT7 binding proteins, we expressed V5-tagged SIRT6 and SIRT7 and pulled down this protein with anti-V5 agarose affinity gel. Sirtuins are a family of NAD-dependent deacetylases which deacetylate not only histones but also a wide range of target proteins. Sirtuins are conserve...
ORGANISM(S): Homo sapiens (Human) 
2014-04-28 | PXD000159 | Pride
Sirt7 Sirt6 Lc-ms/ms 
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