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ProteomicsComprehensive proteomics for Discovery vaccine candidates against Streptococcus equi Infections
Streptococcus equi subspecies equi (S. equi) is a major pathogen which cause strangles, a highly contagious respiratory infection, in horses and other equines.In this study, we discovered potential vaccine candidates using comprehensive proteomics and reverse vaccinology. As the initial step, we div...
ORGANISM(S): Streptococcus equi subsp. equi 4047 
2021-08-06 | PXD025152 | Pride
Secretory proteome Label-free Membrane proteome Streptococcus equi Extracellular vesicle Whole cell lysate Lc-ms Comprehensive proteome 
ProteomicsComprehensive proteomics for Discovery vaccine candidates against Streptococcus equi Infections
Streptococcus equi subspecies equi (S. equi) is a major pathogen which cause strangles, a highly contagious respiratory infection, in horses and other equines. In this study, we purified the extracellular vesicles (EVs) of S. equi ATCC 39506 and evaluated them as vaccine candidates against S. equi i...
ORGANISM(S): Mus musculus (Mouse) Streptococcus equi subsp. equi 
2021-08-06 | PXD025527 | Pride
Label-free Lc-ms Streptococcus equi Extracellular vesicle Immunoprecipitation-ms 
UnknownClinical Usefulness of Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry Method for Low Serum Testosterone Measurement.
Not available
S-EPMC9467846 | biostudies-literature
TranscriptomicsSTAT3-mediated CD133 upregulation promotes hepatocellular carcinoma
We identified a novel mechanism by which IL-6/STAT3 signaling up-regulates CD133 expression and promotes HCC progression. STAT3 activation upregulates the expression of CD133 during liver carcinogenesis. Targeting STAT3-mediated CD133 overexpression may represent a promising therapeutic strategy for...
ORGANISM(S): Homo sapiens 
2014-08-08 | E-GEOD-60194 | biostudies-arrayexpress
UnknownClinical application of whole-genome sequencing of solid tumors for precision oncology.
Not available
S-EPMC11371929 | biostudies-literature
TranscriptomicsNegative-Pressure Induces p120-Catenin Dependent Adherens Junction Disassembly
Background: Negative-pressure wound therapy has become widely available in modern chronic wound cares. Accelerated keratinocyte (HaCaT cell) movements and decreased E-cadherin expressions induced by the applied negative pressure gradient of 125 mmHg (NP) have been reported in previous studies. Howev...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-70512 | biostudies-arrayexpress
UnknownThe genetic determinants of recurrent somatic mutations in 43,693 blood genomes.
Not available
S-EPMC10132750 | biostudies-literature
UnknownAberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.
Not available
S-EPMC10360040 | biostudies-literature
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