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UnknownIn utero particulate matter exposure in association with newborn mitochondrial ND4L10550A>G heteroplasmy and its role in overweight during early childhood.
Not available
S-EPMC9484069 | biostudies-literature
GenomicsWhole-exome sequencing of breast cancer metastasis and corresponding blood samples
This study included samples from metastatic breast cancer patients who underwent a biopsy in the context of SAFIR01 (NCT01414933), SAFIR02 (NCT02299999), SHIVA (NCT01771458) and MOSCATO (NCT01566019) prospective trials. These French multicentre trials used high throughput genome analysis on fresh fr...
EGAS00001001695 | EGA
TranscriptomicsB-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer
Anaysis of the response to different therapeutic agents at the transcriptional level. The design of the experiment allows to determine how the comnination target therapy (Rapamycin + PD0325901) treatment shifted the transcriptome towards a less aggressive or even a wild type phenotype. It also allow...
ORGANISM(S): Mus musculus 
2012-07-18 | E-GEOD-39190 | biostudies-arrayexpress
TranscriptomicsCross-species analysis of genome-wide regulatory networks identifies a synergistic dependency between FOXM1 and CENPF that drives prostate cancer malignancy
Analysis of the transcriptome of mouse models of prostate cancer to assemble a mouse prostate cancer interactome. To assemble the mouse prostate cancer interactome, we collected 13 distinct mice or genetically-engineered mouse models (GEMMs), which together represent the full spectrum of prostate ca...
ORGANISM(S): Mus musculus 
2014-05-12 | E-GEOD-53202 | biostudies-arrayexpress
Genomicsena-DATASET-IGR-28-10-2016-14:22:46:181-287 - samples
Whole-exome sequencing (WES) of 216 breast cancer metastasis-normal pairs from patients who underwent a biopsy in the context of the SAFIR01, SAFIR02, SHIVA or MOSCATO prospective trials (France).
EGAD00001002747 | EGA
GenomicsData Access Committee for the Metastatic Breast Cancer Whole-exome sequencing study
Data Access Committee EGAC00001000434
EGAC00001000434 | EGA
TranscriptomicsExpression profiling of brain structures of dependent and non-dependent rats self-administering alcohol and naive controls
Rats were trained to orally self-administer alcohol in a concurrent, two-lever, free-choice contingency using a modification of the sweet solution fading procedure (O'Dell et al., 2004; Roberts et al., 2000; Vendruscolo et al., 2012). Following acquisition of self-administration, rats were allowed t...
ORGANISM(S): Rattus norvegicus 
2014-11-13 | E-GEOD-60966 | biostudies-arrayexpress
TranscriptomicsETV4 promotes metastasis in response to combined activation of PI3kinase and RAS signaling in a mouse model of advanced prostate cancer
Analysis of the transcriptome of mouse models of prostate cancer. NP (Nkx3.1CreERT2/+; Ptenfloxed/floxed) mice develop non-metastatic tumors while NPK (Nkx3.1CreERT2/+; Ptenfloxed/floxed; KrasG12D/+) mice develop metastatic tumors The NPK mice are also analyzed at early and late stages of tumorigene...
ORGANISM(S): Mus musculus 
2013-07-23 | E-GEOD-47697 | biostudies-arrayexpress
TranscriptomicsDual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model
Analyses of differential gene expression analyses from intact versus castrated Nkx3.1CE2/+ or Nkx3.1CE2/+; Ptenf/f mice Total RNA isolated form phenotypically wild-type (intact) Nkx3.1CE2/+ (n = 3), intact Nkx3.1CE2/+; Ptenf/f (n = 6), and castrated Nkx3.1CE2/+; Ptenf/f (n = 6) prostate. Please con...
ORGANISM(S): Mus musculus 
2012-07-03 | E-GEOD-39054 | biostudies-arrayexpress
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