Left ventricular tissue

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Organisms

Mus musculus (110)
Homo sapiens (46)
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Oryctolagus cuniculus (2)
Canis lupus familiaris (2)
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Repository

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Tissue

Heart (58)
Cardiac muscle cell (5)
Cardiac muscle tissue of ventricle (3)
Cardiocyte (3)
Blood cell (2)
Blood plasma (2)
Fibroblast (2)
Heart left ventricle (2)
Macrophage (2)
Brain (1)
Cardiac endothelial cell (1)
Cardiac muscle (1)
Cell culture (1)
Cell suspension culture (1)
Endothelial cell (1)
Extracellular matrix (1)
Fibroblast of cardiac tissue (1)
Left ventricle (1)
Neutrophil (1)
Stem cell (1)
T cell (1)
Ventricular cardiac muscle cell (1)

Disease

Cardiovascular system disease (12)
Heart failure (7)
Myocardial ischemia (5)
Cardiomyopathy (3)
Normal (2)
Aortic valve stenosis (2)
Arrhythmogenic right ventricular cardiomyopathy (2)
Systolic heart failure (2)
Ischemic (1)
Hypertension (1)
TAC operated 5 hours after surgery (1)
Sham surgery (1)
Viral myocarditis (1)
Coronary artery disease (1)
Idiopathic dilated cardiomyopathy (1)
Acute myocardial infarction (1)
Heart disease (1)
Hypertrophic cardiomyopathy (1)
Migraine (1)
Myocardial infarction (1)
Myopathy (1)
Type 1 diabetes mellitus (1)

Technology Type

Mass Spectrometry (67)
Shotgun proteomics (34)
Bottom-up proteomics (18)
Data-dependent acquisition (11)
Data-independent acquisition (6)
Mass spectrometry assay (5)
Mass spectrometry (3)
Affinity purification coupled with mass spectrometry proteomics (2)
DiaPASEF (2)
SRM/MRM (2)
SWATH MS (2)
HiSeq X Ten (ILLUMINA) (1)
Illumina MiSeq (1)
All-ion fragmentation (1)
Gel-based experiment (1)
HDMSE (1)
Metaproteomics (1)
Proteogenomics (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (14)
Illumina HiSeq 4000 (10)
NextSeq 500 (10)
NextSeq 2000 (5)
NextSeq 550 (5)
Illumina HiSeq 2000 (5)
Illumina HiSeq 2500 (4)
Single nuclei were captured using the 10x Genomics Chromium Controller. (2)
Illumina NovaSeq X (2)
LTQ Orbitrap Velos (Thermo Scientific) (2)
Q Exactive (2)
QExactive (2)
Liquid Chromatography MS - alternating - hilic (2)
Liquid Chromatography MS - positive - hilic (2)
HISeq2500 (1)
Affymetrix GeneChip Scanner 3000 7G (1)
428 [Affymetrix] (1)
DNA Microarray Scanner BA [Agilent Technologies] (1)
Illumina HiSeq 1000 (1)
MinION (1)
BGISEQ-500 (1)
HiSeq X Ten (1)
Illumina HiSeq 3000 (1)
Orbitrap Fusion (1)
Q Exactive HF (1)
Q Exactive HF-X (1)
Synapt G2 HDMS (1)
Thermo Q Exactive Hybrid Quadrupole-Orbitrap (1)
TimsTOF fleX MALDI-2 (1)
Liquid Chromatography MS - negative (1)

Publication Date

2026 (59)
2010 (31)
2024 (30)
2023 (30)
2025 (28)
2022 (25)
2014 (24)
2013 (19)
2020 (17)
2015 (17)
2021 (16)
2018 (16)
2016 (16)
2011 (15)
2019 (13)
2012 (12)
2009 (11)
2017 (9)
2008 (9)
2007 (8)
2006 (8)
2005 (6)
2004 (2)

CHEBI ID

CHEBI:136242 (1)
CHEBI:136221 (1)
CHEBI:73208 (1)
CHEBI:136217 (1)
CHEBI:136174 (1)
CHEBI:136172 (1)
CHEBI:136165 (1)
CHEBI:136155 (1)
CHEBI:136159 (1)
CHEBI:134573 (1)
CHEBI:134555 (1)
CHEBI:134554 (1)
CHEBI:134553 (1)
CHEBI:136350 (1)
CHEBI:136349 (1)
CHEBI:136346 (1)
CHEBI:136344 (1)
CHEBI:136342 (1)
CHEBI:136341 (1)
CHEBI:136339 (1)
CHEBI:136338 (1)
CHEBI:136336 (1)
CHEBI:136334 (1)
CHEBI:136332 (1)
CHEBI:136331 (1)
CHEBI:136328 (1)
CHEBI:136326 (1)
CHEBI:136324 (1)
CHEBI:136325 (1)
CHEBI:136323 (1)

Metabolite Name

Tricyclo[3.3.1.1(3,7)]decane-1-carboxamide, n-[2-(benzoylamino)-6-benzothiazolyl]- (1)
Timosaponin a-iii (1)
S-adenosyl-l-methionine (1)
Pcb 52 (1)
N-(tert-butyl)benzenesulfonamide (1)
N-(6-aminohexyl)-1-chloronaphthalene-5-sulfonamide (1)
N-(2-aminoethyl)-5-isoquinolinesulfonamide (1)
Arg-Pro-Arg (1)
6-bromoquinolin-2-ol (1)
4,7-dichloroquinoline (1)
4,5-epoxy-7z,10z,13z,16z,19z-docosapentaenoic acid, methyl ester (1)
4-(methylamino)-4-(3-pyridyl)butyric acid (1)
2-propylbenzimidazole (1)
2-hydroxy-5-nitrobenzyl alcohol (1)
2-((4r)-4-((3r,5s,9s,10s,13r,14s,17r)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1h-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonic acid (1)
1h-1,2,3-triazole-1-octanamide, n-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)- (1)
1,2-benzenediamine, 4-methyl-n1-(3-phenylpropyl)- (1)
1-nitro-2-phenoxybenzene (1)
1-methyl-2-undecylquinolin-4-one (1)
1-amino-2-ethoxybenzene (1)
(-)-n6-(2-phenylisopropyl)adenosine (1)
Prometryne (1)
N-cyclohexylaniline (1)
4-(4-aminophenoxy)aniline (1)
S-methyl-3-thioacetaminophen (1)
N-acetyl-d-norleucine (1)
N,n-diethyl-3,4-dimethoxybenzamide (1)
Hexadecylacetylglycerol (1)
Flavanone hydrazone (1)
Dl-homocysteine (1)

IsPrivate

False (3)

First Public Date

2026 (45)
2025 (39)
2024 (32)
2014 (24)
2023 (21)
2022 (21)
2019 (13)
2018 (13)
2020 (12)
2021 (10)
2017 (5)
2015 (4)

Modelling Approach

Ordinary differential equation model (3)

Study type

Transcription profiling by array (145)
RNA-seq of coding RNA (44)
RNA-seq of coding RNA from single cells (9)
RNA-seq of total RNA (4)
MicroRNA profiling by high throughput sequencing (3)
Single nucleus RNA sequencing (3)
Animal - One-color microarray (2)
Methylation profiling by array (2)
RNA-seq of non coding RNA (2)
Single-nucleus ATAC-seq (1)
ChIP-chip by tiling array (1)
Human - High-throughput sequencing (1)
Human - One-color microarray (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
Transcription profiling by tiling array (1)
ChIP-chip by array (1)
Genotyping by array (1)
Transcription profiling by RT-PCR (1)
Spatial transcriptomics by high-throughput sequencing (1)
Ribo-seq (1)
Other (1)
ChIP-seq (1)
MicroRNA profiling by array (1)

Release Date

2022 (213)
2021 (213)
2023 (209)
2025 (193)
2020 (160)
2024 (158)
2019 (122)
2018 (122)
2014 (93)
2015 (88)
2016 (86)
2017 (86)
2010 (52)
2013 (48)
2012 (38)
2011 (37)
2026 (36)
2009 (24)
2008 (17)
2007 (12)
2006 (10)
2005 (4)
2004 (1)
2002 (1)
2001 (1)

Lab affiliation

Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (2)
Department of Physiology, Faculty of Science, Charles University, 128 00 Prague, Czechia (2)
Executive Science Officer, BioFrontiers InstituteDistinguished ProfessorProfessor, Howard Hughes Medical Institute MOLECULAR CELLULAR AND DEVELOPMENTAL BIOLOGY CU DENVER SCHOOL OF MEDICINE (2)
Hannover Medical School, Department of Cardiology and Angiology (2)
Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München (2)
The University of Melbourne (2)
Associate Professor, Department of Biomedical Sciences,Affiliated with The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen (1)
BIOCEV, First Faculty of Medicine, Charles University, Prague, Czech Republic (1)
Baker Heart & Diabetes Institute (1)
Centre for Clinical Proteomics, Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Denmark (1)
Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid. (1)
Consultant Cardiologist in Inherited Cardiac Conditions Ã¢â‚¬â€œ Royal Free London Senior Clinical Lecturer Ã¢â‚¬â€œ UCL MRC LHA @UCL 1-19 Torrington Place London UK WC1E 7HB (1)
Core Facility Proteomics, Department of Clinical Medicine, University Medical Center Goettingen, Germany (1)
Department of Analytical Chemistry and CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China (1)
Department of Basic Medical Sciences, University of Arizona College of Medicine, Phoenix, AZ 85004, USA (1)
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark (1)
Department of Cardiology, Medical University Hospital, Heidelberg, Germany (1)
Department of Experimental Pharmacology and 35 Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 36 Martinistrasse 52, 20246 Hamburg, Germany (1)
Department of Functional Genomics Felix-Hausdorff-Str. 8 17489 Greifswald (1)
Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany (1)
Department of Geriatric Cardiology, Hebei General Hospital, No. 348 Heping Road, Xinhua District, Hebei, 050000, China. (1)
Department of Integration of Chinese and Western Medicine, School of Basic Medicine Science, Peking University, China (1)
Department of Internal Medicine, Botucatu Medical School, São Paulo State University, UNESP, SP, Brazil (1)
Department of Laboratory Medicine and Pathology Mayo Clinic, Rochester, Minnesota 55905 United States (1)
Department of Pathophysiology, Mudanjiang Medical University (1)
Department of Pediatrics, Shengjing Hospital of China Medical University (1)
Department of Physiology, Pennsylvania Muscle Institute, Penn Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. (1)
Department of Physiology, University of Toronto Ted Rogers Centre for Heart Research Toronto, Ontario, Canada (1)
Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China. (1)
Department of Systems Pharmacology, Graduate School of Medicine, the University of Tokyo, Japan (1)

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Untargeted Metabolomic Profiling of Left Ventricular Myocardium in a Mouse Model of Diabetic Cardiomyopathy

This study characterizes metabolic alterations in the left ventricular myocardium of a high-fat diet and streptozotocin-induced mouse model of diabetic cardiomyopathy. Untargeted LC–MS/MS metabolomics was performed using a Vanquish UHPLC system coupled to an Orbitrap Exploris 120 mass spectrometer. ...

2026-07-20 | MTBLS15043 | MetaboLights

Non-targeted metabolomics sequencing of cardiac tissue with or without high-valine diet

Non-targeted metabolomics revealed that a high-valine diet affected amino acid synthesis, biometabolism, and glycolipid metabolism in cardiac tissue from hypertensive animal model.

2026-09-26 | MTBLS15818 | MetaboLights

mRNA sequencing of two brain regions (prefrontal cortex and hippocampus) and left myocardial tissue in mice with chronic heart failure vs. sham-operated control mice

After induction of ischemic chronic heart failure (CHF), mice exhibited depression-like behavior, in terms of increased anhedonia, and decreased both exploratory activity and interest in novelty. On histology, ischemic CHF mice showed no alterations in overall cerebral morphology. To further evaluat...

ORGANISM(S): Mus musculus

2015-02-20 | E-GEOD-55280 | biostudies-arrayexpress

Transcription profiling of feft ventricle in three genetic rat models of hypertension

Left ventricle gene expression was analyzed in three models of hypertension in order to clarify the molecular mechanisms associated with left ventricular hypertrophy. Transgenic heterozygous TGR(mRen2)27 rats, overexpressing the mouse renin gene, and their littermate negative controls, spontaneously...

ORGANISM(S): Rattus norvegicus

2006-08-31 | E-MEXP-357 | biostudies-arrayexpress

Distinctive Profile of IsomiR Expression and Novel MicroRNAs in Rat Heart Left Ventricle

MicroRNAs (miRNAs) are single-stranded non-coding RNAs that negatively regulate target gene expression through mRNA cleavage or translational repression. There is mounting evidence that they play critical roles in heart disease. The expression of known miRNAs in the heart has been studied at length ...

ORGANISM(S): Rattus norvegicus

2014-03-28 | E-GEOD-56300 | biostudies-arrayexpress

Molecular remodeling of ion channels, exchangers and pumps in atrial and ventricular myocytes in ischemic cardiomyopathy: left ventricle DCM

We wanted to see whether the set of affected genes in ischemic cardiomyopathy (ICM) is the same or different as compared to dilated cardiomyopathy (DCM). To find this out, we placed the single DCM sample on the same microarray slide with the ICM samples. Analysis of microarray data with ICM samples ...

ORGANISM(S): Homo sapiens

2010-06-17 | E-GEOD-17530 | biostudies-arrayexpress

Proteomic profiling of human left ventricular extracellular matrix

Proteomic analysis of decellularized human left ventricular extracellular matrix used for engineering humanized heart tissues. Data were generated to characterize ECM composition supporting cardiotoxicity assessment in a recellularized engineered heart tissue platform.

ORGANISM(S): Homo sapiens (Human)

2026-04-27 | PXD074354 | Pride

Transcriptional profiling of left ventricle and peripheral blood cells in rats with post-myocardial infarction

Myocardial infarction (MI) often results in left ventricular (LV) remodeling followed by heart failure (HF). It is of great clinical importance to understand the molecular mechanisms that trigger transition from compensated LV injury to HF and to identify relevant diagnostic biomarkers. In this stud...

ORGANISM(S): Rattus norvegicus

2013-11-15 | E-GEOD-47495 | biostudies-arrayexpress

Left ventricular myocardial transcriptomic profiling for target discovery in a rat model of pressure overload-induced heart failure

Left ventricular myocardial transcriptomic profiling was performed in rats subjected to transverse aortic constriction (TAC)-induced heart failure and sham-operated controls to investigate gene expression changes associated with pressure overload-induced cardiac remodeling. The dataset was used in s...

ORGANISM(S): Rattus norvegicus

2026-06-11 | E-MTAB-17114 | biostudies-arrayexpress

Transcription profiling of human left ventricular apex samples

19 paired human left ventricular apex samples were harvested at the time of implant of a left ventricular assist device (PRE) and at the time of explant (POST). The cohort included patients that were clinically classified as ischemic (I) showing evidence of coronary artery disease, non-ischemic (N) ...

ORGANISM(S): Homo sapiens

2007-10-02 | E-GEOD-974 | biostudies-arrayexpress

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