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TranscriptomicsTranscription profiling of human monocytes infected with adenovirus expressing either c-Myb or v-Myb
The transcriptional activities of c-Myb and its oncogenic variant v-Myb were compared by expressing them in primary human monocytes using recombinant adenovirus vectors. All the samples were compared to cells infected with a control adenovirus expressing only GFP. The results showed that v-Myb, whi...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-2816 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human MCF7 cells infected with adenovirus expressing c-Myb, v-Myb or the hybrid construct, 3MutC
The transcriptional activities of c-Myb and its oncogenic variant v-Myb were compared by expressing them in human MCF7 cells using recombinant adenovirus vectors. A hybrid construct, 3Mutc, which is a variant of c-Myb harboring three v-Myb-derived DNA binding domain mutations was also analyzed. All...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-2815 | biostudies-arrayexpress
ProteomicsNAPT, an unbiased approach for sequential analysis of protein N- and C- terminome
Robust analysis of both protein N- and C-termini can reveal novel N- and C-degrons that modify protein stability and shape the eukaryotic proteome. Herein, we designed a workflow, termed LysargiNase-assisted Analysis of Protein N- and C-Terminome (NAPT) by sequential and selective separating N- and ...
ORGANISM(S): Homo Sapiens 
2022-04-11 | PXD030791 |
UnknownComparative transcriptomic analysis of the flower induction and development of the Lei bamboo (Phyllostachys violascens).
Not available
S-EPMC6929269 | biostudies-literature
TranscriptomicsTranscription profiling of human wild type or domain swap mutants of A-Myb and c-Myb transcription factors in MCF-7 cells or pimary lung epithelial cells or fibroblasts Myb specificity determinants
Recombinant adenovirus vectors were used to express wild type or domain swap mutants of A-Myb and c-Myb transcription factors in MCF-7 cells or pimary lung epithelial cells or fibroblasts. The results show that Myb proteins have extreme context specificity and identify sub-domains responsible for th...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1318 | biostudies-arrayexpress
ProteomicsHuman lung cancer cells-MS for SNHG3 c.1746A>I editing
Adenosine-to-inosine (A-to-I) RNA editing is a critical post-transcriptional modification that enhances tumor genome diversity and contributes to cancer progression. In non-small cell lung cancer (NSCLC), while specific A-to-I editing events have been identified, their functional mechanisms and clin...
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD067139 | Pride
Human Lung Snhg3 
ProteomicsSuppression of cytochrome c oxidase subunit 4 isoform 1 expression inhibits replication of highly pathogenic H5N1 influenza virus
Human infection with highly pathogenic H5N1 influenza virus causes severe respiratory diseases. Currently, the drugs against H5N1 are limited to virus-targeted inhibitors. However, drug resistance caused by these inhibitors is becoming a serious threat to global public health. An alternative strateg...
ORGANISM(S): Canis Lupus 
2022-01-27 | PXD031293 |
GenomicsIdentification of N6-adenine methylation in C. elegans DNA
In mammalian cells, DNA methylation on the 5th position of cytosine (5mC) plays an important role as an epigenetic mark. However, DNA methylation was considered to be absent in C. elegans because of the lack of detectable 5mC as well as homologs of the cytosine DNA methyltransferases. Here, using mu...
ORGANISM(S): Caenorhabditis elegans 
2015-05-05 | E-GEOD-66504 | biostudies-arrayexpress
MetabolomicsMetabolic Responses of a Model Green Microalga Euglena gracilis to Different Environmental Stresses

Euglena gracilis, a green microalga known as a potential candidate for jet fuel producers and new functional food resources, is highly tolerant to antibiotics, heavy metals and other environmental stresses. Its cells contain many high-value products, including vitamins, amino acids, pigm...

2022-08-16 | MTBLS2878 | MetaboLights
UnknownDrug screening in pharmaceutical and forensic applications using extractive-liquid sampling electron ionization-mass spectrometry (E-LEI-MS).
Not available
S-EPMC12368195 | biostudies-literature
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