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Agrobacterium tumefaciens-mediated genetic transformation has been routinely used in rice for more than a decade. However, the transformation efficiency of the indica rice variety is still unsatisfactory and much lower than that of japonica cultivars. Further improvement on the transformation effici...
ORGANISM(S): Oryza sativa Japonica Group 
The present study aimed to investigate the antibacterial effect and mechanism of a carvacrol-rich Oregano essential oil (OEO) on the inactivation of Staphylococcus aureus. A label-free proteomic analysis was applied to analyze the regulatory networks of S. aureus in response to 1/2 MIC OEO-treatment...
ORGANISM(S): Staphylococcus aureus 
2021-11-02 | PXD028357 | Pride
ALS is a devastating motor neuron disease. Protein O-linked β-N-acetylglucosamine (O-GlcNAc) modification has been found to affect the processing of several important proteins implicated in ALS. However, the O-GlcNAcylated proteome remains unexplored during ALS progression. Herein, we probed the dyn...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD059664 | Pride
XAB2 is a multi-functional protein participating processes including transcription, splicing, DNA repair and mRNA export. Here we report POLR2A as a major target gene down-regulated after XAB2 depletion. XAB2 depletion led to severe splicing defects of POLR2A with significant intron retention. Such ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-13 | PXD012552 | Pride
Two genetic selection systems that couple metabolite hydroxylation or methylation of small molecules to growth of Escherichia coli are presented in this study. One system targets pterin-dependent hydroxylation (tBPt) while another focuses on S-adenosylmethionine-dependent methylation (SAM). Using ad...
ORGANISM(S): Escherichia coli BW25113 
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
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