Leishmania infantum

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Unknown (1088)
Genomics (148)
Transcriptomics (48)
Proteomics (34)
Models (2)
Other (2)
Metabolomics (2)

Organisms

Mycobacterium tuberculosis SP7 (33)
Mycobacterium tuberculosis SP10 (33)
Mycobacterium tuberculosis SP13 (33)
Mycobacterium tuberculosis SP22 (33)
Chlamydomonas reinhardtii (33)
Enterococcus mundtii CRL35 (33)
Oncorhynchus tshawytscha (33)
Pseudomonas canadensis (33)
Pseudomonas aeruginosa PAO1H2O (33)
Human alphaherpesvirus 1 strain 17 (33)
Mycobacterium tuberculosis SP1 (33)
Marchantia polymorpha subsp. ruderalis (33)
Methylocystis sp. (33)
Exiguobacterium sp. SH31 (33)
Palaemonetes sp. common grass shrimp associated circular virus (33)
Amaranthus tricolor (33)
Spirochaeta sp. ELBA (33)
Leishmania infantum (24)
Leishmania major (10)
Mus musculus (10)
Homo sapiens (8)
Leishmania donovani (4)
Leishmania tarentolae (3)
Leishmania (3)
Canis lupus familiaris (3)
Leishmania chagasi (2)
synthetic construct (2)
Leishmania braziliensis (1)
Leishmania infantum JPCM5 (1)
Macaca mulatta (1)

Organisms

Leishmania infantum (21)
Leishmania major (11)
Mus musculus (9)
Homo sapiens (5)
Leishmania infantum JPCM5 (4)
Leishmania donovani (3)
Canis lupus familiaris (3)
Leishmania chagasi (2)
Phlebotomus perniciosus (2)
Leishmania RNA virus 2 (1)
Macaca mulatta (1)

Repository

ENA (142)
geo (34)
pride (33)
biostudies-arrayexpress (22)
BioModels (2)
MetaboLights (2)
iProX (1)

Tissue

Blood plasma (4)
Promastigote (2)
Blood serum (2)
Cell culture (2)
Diploid cell (1)
Permanent cell line cell (1)
Urine (1)
Thymus (1)
Whole body (1)

Disease

Leishmaniasis (9)
Visceral leishmaniasis (6)
N/A (culture-derived) (1)
Cutaneous leishmaniasis (1)
Trypanosomiasis (1)

Technology Type

Mass Spectrometry (33)
Shotgun proteomics (15)
Affinity purification coupled with mass spectrometry proteomics (6)
Bottom-up proteomics (5)
Gel-based experiment (4)
Data-dependent acquisition (3)
Mass spectrometry (2)
Data-independent acquisition (2)
MSE (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
SWATH MS (1)

Instrument Platform

Illumina HiSeq 2500 (4)
Illumina NovaSeq X (1)
NextSeq 2000 (1)
DNBSEQ-T7 (1)
Liquid Chromatography MS - alternating - hilic (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - positive - hilic (1)
LTQ-Orbitrap (1)

Publication Date

2022 (12)
2016 (10)
2026 (8)
2018 (7)
2008 (7)
2020 (6)
2024 (6)
2010 (6)
2025 (5)
2009 (5)
2011 (4)
2019 (4)
2023 (4)
2021 (3)
2014 (2)
2013 (2)
2007 (1)
2012 (1)

CHEBI ID

CHEBI:140755 (1)
CHEBI:17844 (1)
CHEBI:16938 (1)
CHEBI:17835 (1)
CHEBI:28013 (1)
CHEBI:68819 (1)
CHEBI:27469 (1)
CHEBI:17869 (1)
CHEBI:5445 (1)
CHEBI:72715 (1)
CHEBI:28816 (1)
CHEBI:17981 (1)
CHEBI:33942 (1)
CHEBI:16946 (1)
CHEBI:17234 (1)
CHEBI:15824 (1)
CHEBI:48928 (1)
CHEBI:28842 (1)
CHEBI:171116 (1)
CHEBI:17111 (1)
CHEBI:30797 (1)
CHEBI:73024 (1)
CHEBI:16349 (1)
CHEBI:16217 (1)
CHEBI:16411 (1)
CHEBI:37550 (1)
CHEBI:36274 (1)
CHEBI:15699 (1)
CHEBI:17066 (1)
CHEBI:17196 (1)

Metabolite Name

O-acetylcarnitine (1)
Cervonyl carnitine (1)
Timnodonyl carnitine (1)
Sphingosine-1-phosphate (1)
L-citrulline (1)
O-acetyl-l-serine (1)
L-homoserine (1)
L-kynurenine (1)
4-hydroxy-2-quinolinecarboxylic acid (1)
Chenodeoxyglycocholate (1)
L-asparagine (1)
Sn-glycero-3-phosphocholine (1)
L-glutamine (1)
L-tryptophan (1)
L-histidine (1)
D-Glucono-1,5-lactone 6-phosphate (1)
Indole-3-acetate (1)
Ribose 1,5-bisphosphate (1)
Erythrose 4-phosphate (1)
Glucono-1,5-lactone (1)
2-Phospho-D-glycerate (1)
Ribose 5-phosphate (1)
Sedoheptulose 7-phosphate (1)
Glyceraldehyde 3-phosphate (1)
Fructose 1,6-bisphosphate (1)
Linoelaidyl carnitine (1)
6-Phospho-D-gluconate (1)
5-Phospho-alpha-D-ribose 1-diphosphate (1)
Ribose (1)
Cytosine (1)

IsPrivate

False (2)

First Public Date

2018 (23)
2022 (19)
2025 (11)
2020 (11)
2014 (11)
2026 (10)
2024 (10)
2019 (10)
2023 (9)
2013 (8)
2021 (7)
2017 (5)
2016 (5)
2012 (2)
2015 (1)

Classification

protozoa (41)
viruses (1)

Modelling Approach

Constraint-based model (2)

Modification

42.010565 (1)
15.994915 (1)
57.021464 (1)

Study type

Transcription profiling by array (10)
RNA-seq of coding RNA (6)
Unknown experiment type (2)
Comparative genomic hybridization by array (2)
DNA-seq (1)
RNA-seq of total RNA (1)

Release Date

2022 (113)
2020 (105)
2021 (98)
2025 (90)
2023 (79)
2024 (76)
2018 (75)
2017 (75)
2019 (72)
2016 (62)
2015 (50)
2014 (48)
2013 (29)
2012 (28)
2011 (26)
2010 (20)
2026 (14)
2008 (11)
2009 (9)
2006 (6)
2007 (5)
2004 (5)
2003 (4)
2005 (3)
2001 (3)
2002 (2)
2000 (1)
1999 (1)

Lab affiliation

Faculty of Biology, Technion (2)
VetMedZg Laboratory,Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, UK (2)
Department of Microbiology, Aggeu Magalhaes Institute, Brazil (1)
IMVZ, Friedrich-Loeffler-Institut, Greifswald (1)
Laboratório de Pesquisa em Leishmanioses, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, RJ, Brasil (1)
Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, United Kingdom (1)
1. Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada; 2. University of Victoria Genome BC Proteomics Centre, University of Victoria, Victoria, British Columbia, Canada; 3. Gerald Bronfman Department of Oncology, Jewish General Hospital, Montreal, Quebec, Canada; 4. Segal Cancer Proteomics Centre, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada (1)
Universite Laval-CHU de Quebec Research Center (1)
INVESTIGADOR PRINCIPAL (1)
University of Montréal (1)
Microbiology departament, Aggeu Magalhães Institute, Brazil. (1)
WCAIR, School of Life Sciences, BCDD, University of Dundee (1)
Department of Genetics and Evolution, Federal University of São Carlos, São Carlos, Brazil. (1)
CHU de Quebec Research Center-Laval University 2705 Laurier Blvd., Quebec (QC), Canada G1V 4G2 Phone: (418) 525-4444, ext. 47608; Fax: (418) 654-2715 (1)
Laboratory of Microbiology, Parasitology and Hygiene, University of Antwerp (1)
Departamento de Fisiologia e Biofisica, Universidade Federal de Minas Gerais (1)
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal Serviço de Microbiologia, Departamento de Ciências Biológicas, Faculdade de Farmácia da Universidade do Porto, Portugal (1)
i3S - Institute for Research and Innovation in Health (1)
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905 (1)
Faculty of Biology, Technion - Israel Institute of Technology, Haifa 32000, Haifa, Israel (1)
Chronic Disease Program (UFIEC), Instituto de Salud Carlos III, Majadahonda, Madrid, Spain (1)
UMR177 INTERTRYP, IRD, Montpellier, France (1)
Mercer University School of Medicine, Department of Medical Sciences (1)
Chronic Disease Program (UFIEC), Instituto de Salud Carlos III, Majadahonda, Spain. (1)
Department of Genetics and Evolution, Federal University of São Carlos, São Paulo, Brazil (1)
Charles University in Prague, BIOCEV Průmyslová 595 252 50 Vestec Czech Republic (1)
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 USA (1)
733 N. Broadway Room 527, Miller Research Building Baltimore MD 21205 USA (1)
Max Planck Intitute of Biochemistry (1)
Faculty of Science, Department of Chemistry, B-205 İzmir Institute of Technology (IzTech) (1)

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Transcriptional analysis of wild-type Leishmania species between both stages using full-genome DNA microarrays

Transcriptional analyses of L. infantum promastigote compared to L. infantum intracellular amastigote, and L. major promastigote compared to L. major intracellular amastigote The full-genome DNA microarray includes one 70mer-oligonucleotide probe for each gene of L. infantum and for each gene of L....

ORGANISM(S): Leishmania major

2008-05-28 | E-GEOD-10407 | biostudies-arrayexpress

Whole-genome comparative RNA expression profiling of axenic and intracellular amastigote forms of Leishmania infantum

Transcriptional analysis of L. infantum promastigote compared to L. infantum intracellular amastigote and transcriptional analysis of L. infantum promastigote compared to L. infantum axenic amastigote. The full-genome DNA microarrays includes one 70-oligonucleotides probe for each gene of L.infantum...

ORGANISM(S): Leishmania infantum

2010-05-14 | E-GEOD-13983 | biostudies-arrayexpress

Methotrexate resistant Leishmania strains

This SuperSeries is composed of the following subset Series: GSE9947: Transcriptional analysis of Leishmania infantum methotrexate resistant strains using full-genome DNA microarrays GSE9948: Transcriptional analysis of Leishmania major methotrexate resistant strains using full-genome DNA microarray...

ORGANISM(S): Leishmania infantum

2010-05-25 | E-GEOD-9949 | biostudies-arrayexpress

Transcriptional analysis of Leishmania infantum antimony resistant strains using full-genome DNA microarrays

The aim of the experiment is to detect any gene expression modulation in an antimony resistant L.infantum Sb2000.1 strain compared to an antimony sensitive L.infantum WT strain. We want to identify the modulated genes associated with an antimony resistant phenotype. The Sb2000.1 resistant strain use...

ORGANISM(S): Leishmania infantum

2009-08-15 | E-GEOD-16965 | biostudies-arrayexpress

Genetic introgression and transcriptomic plasticity are associated with enhanced Leishmania infantum pathogenicity causing human cutaneous leishmaniasis in Tunisia

The protozoan parasite Leishmania infantum exhibits significant genetic variability among isolates, influencing disease manifestation and treatment response. Although L. infantum is classically described as the causative agent of Visceral Leishmaniasis (VL) – often associated with immune deficiency,...

ORGANISM(S): Leishmania infantum

2026-09-17 | E-MTAB-16364 | biostudies-arrayexpress

Transcriptional analysis of Leishmania infantum methotrexate resistant strains using full-genome DNA microarrays

Transcriptional analysis of the drug resistant strain L. infantum MTX20.5 compared to the wild-type strain The full-genome DNA microarrays includes one 70-oligonucleotides probe for each gene of L. infantum Keywords: drug resistance Two-condition experiment, resistant strain MTX20.5 vs wild-type. Fo...

ORGANISM(S): Leishmania infantum

2010-05-25 | E-GEOD-9947 | biostudies-arrayexpress

Metabolic Reprogramming During Purine Stress in the Protozoan Pathogen Leishmania donovani

The ability of Leishmania to survive in their insect or mammalian host is dependent upon an ability to sense and adapt to changes in the microenvironment. However, little is known about the molecular mechanisms underlying the parasite response to environmental changes, such as nutrient availability....

ORGANISM(S): Leishmania donovani

2014-02-01 | E-GEOD-48394 | biostudies-arrayexpress

Mass spectrometry analysis of the Skp1 and Cullin1 interactome in Leishmania infantum

Leishmania infantum is the causative agent of visceral leishmaniasis in Latin America, a lethal disease if misdiagnosed or left untreated. The ubiquitin proteasome system (UPS) is the main regulator of intracellular proteolysis in eukaryotes and is required for parasite's to life cycle and infectio...

ORGANISM(S): Leishmania infantum

2024-07-01 | PXD051961 | Pride

Comparative genomic hybridization of strains of Leishmania infantum, Leishmania major and Leishmania tarentolae

The genomic DNAs of strains JPCM5 and 263 of L. infantum, strains LV39 and Friedlin of L. major and strains Parrot-TarII and S125 of L. tarentolae were used in comparative genomic hybridizations to reveal the intra-species and inter-species gene content, and to validate L. tarentolae Parrot-TarII ge...

ORGANISM(S): Leishmania tarentolae

2011-10-20 | E-GEOD-27184 | biostudies-arrayexpress

Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism, lipid transport and oxidative stress response

Amphotericin B is increasingly used in treatment of leishmaniasis. Here, fourteen independent lines of Leishmania mexicana and one L. infantum line were selected for resistance to either amphotericin B or the related polyene antimicrobial, nystatin. Sterol profiling revealed tha...

2022-09-22 | MTBLS2744 | MetaboLights

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