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We investigated changes in transcriptome of Drosophila female guts in wild-type (w1118) flies and p38c mutant flies (p38c7B1) aged 3-5 days.
ORGANISM(S): Drosophila melanogaster 
Drosophila larvae were infected with Erwinia bacteria (Ecc15) by introducing concentrated bacterial pellet into the fly medium. The tracheae were dissected 24h later. Three genotypes of larvae were compared: wt (CantonS), RelE20 and PGRP-LA, each present in unchallenged and infected conditions. 3 in...
ORGANISM(S): Drosophila melanogaster 
Using an in-depth Mass Spectrometry based proteomics approach, we provide a comprehensive characterization of the hemolymphatic proteome of adult flies upon bacterial infection. We detected and quantified changes in abundance of several known immune regulators and effectors, including multiple antim...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-05-07 | PXD058897 | Pride
We investigated the effect of Spiroplasma infection on Drosophila hemolymph protein content using Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS). To this end, we extracted total hemolymph from uninfected and infected 10 days old females. At this age, Spiroplasma is already present at high...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-05-04 | PXD024340 | Pride
To understand the effects of the microbiome of Drosophila melanogaster on host gene expression, we compared the transcriptome of guts from conventionally reared flies to their axenically (germ-free)-reared counterparts. Our analysis used dissected intestines from 4-7 day-old adult females and includ...
ORGANISM(S): Drosophila melanogaster 
In this strudy, we seek out new chimeric RNA in RNA-seq data from acute myeloid leukemia (AML) patient cells as new biomarkers to improve diagnosis and prognosis in cancer. Total RNA were extracted from bone marrow or peripheral blood mononuclear cells in three AML patients. polyA+ cDNAs were sequen...
ORGANISM(S): Homo sapiens 
Pollinators are of crucial importance for maintaining biodiversity in ecosystems and for agriculture, including the Buff-tailed bumblebee Bombus terrestris. The health decline in these populations is thought to be linked to various abiotic and biotic stressors. In the hope of protecting these popula...
ORGANISM(S): Bombus terrestris (Buff-tailed bumblebee) (Apis terrestris) 
2023-05-10 | PXD035224 | Pride
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