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An Hodgkin Lymphoma cell line have been treated with an LNA inhibitor for miR-9 or with a scramble LNA to identify miR-9 regulated pathways that could be important for Hodgkin Lymphoma pathogenesis. L428 cells were transfected with a miR-9 LNA inhibitor or a scrambled LNA. Total RNA was harvested 9 ...
ORGANISM(S): Homo sapiens 
Cancer therapy resistance, whether pre-existing or arising upon acquisition of de novo mutations and via non-genetic adaptation, is still a clinical challenge. Multiple anticancer drugs are thought to cause cell death via increasing mitochondrial ROS which are a bioproduct of oxidative phosphorylati...
ORGANISM(S): Homo sapiens (Human) 
2024-09-20 | PXD047963 | Pride
Environmental cues within the tumor microenvironment (TME) affect tumor heterogeneity and plasticity, ultimately influencing therapy responses. Recent studies have shown that cancer stem cell niches are located near blood vessels and thus may be exposed to abrupt changes in the osmotic conditions. H...
ORGANISM(S): Homo sapiens (Human) 
2026-05-31 | PXD060369 | Pride
TIG3 TERT/?B-RAF:ER cells were treated with 500 nM 4-OHT
ORGANISM(S): Homo sapiens 
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