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ProteomicsUBA80 and UBA52 regulate DNA damage repair by targeting RNF168-dependent ubiquitination of H2A/H2AX
Tandem affinity purification of RNF168 and various RNF168 mutants to identify interacting proteins involved in DNA damage repair.
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD037840 | Pride
Dna damage Rnf168 Ubiquitin 
ProteomicsScreen Identifies DYRK1B Network as Mediator of Transcription Repression on Damaged Chromatin
The uploaded data are described within "Screen Identifies DYRK1B Network as Mediator of Transcription Repression on Damaged Chromatin". In short, peptides from RPE1 epithelial cells with either normal expression of DYRK1B, over expression, of knockout of the kinase were TMT11 plex labeled and enrich...
ORGANISM(S): Homo sapiens (Human) 
2020-06-18 | PXD019102 | Pride
Human Epithelial Tmt Phosphopeptide Cell culture 
ProteomicsNuclear F-actin Assembly on Damaged Chromatin is Regulated By DYRK1A and Spir1 Phosphorylation
The uploaded data are described within "DYRK1A promotes nuclear F-actin assembly to effect DSB repair metabolism". Peptides from RPE1 epithelial cells with either, over expression of DYRK1A, normal expression of DYRK1A, or knockout of DYRK1A were labeled with TMTpro-16 reagents and phosphopeptides e...
ORGANISM(S): Homo sapiens (Human) 
2024-07-19 | PXD031714 | Pride
Dyrk1a  dsb repair  spir1  dsb mobility  actin dynamics 
UnknownUpdate on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited.
Not available
S-EPMC3286387 | biostudies-literature
UnknownThe benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial.
Not available
S-EPMC3386495 | biostudies-literature
UnknownEffect of alteplase on the CT hyperdense artery sign and outcome after ischemic stroke.
Not available
S-EPMC4731690 | biostudies-literature
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