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MetabolomicsA Metabonomic Comparison of Human Serum and Plasma Subtypes Using Untargeted NMR Spectroscopy and UPLC-MS (NMR assays)
INTRODUCTION: Differences in the metabolite profiles between serum and plasma are incompletely understood. OBJECTIVES: To evaluate metabolic profile differences between serum and plasma and among plasma sample subtypes. METHODS: We analyzed serum, platelet rich plasma (PRP), platelet poo...
2018-07-25 | MTBLS470 | MetaboLights
MetabolomicsImpact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository

INTRODUCTION: Acute lymphoblastic leukemia (ALL) is among the most common cancers in children. With improvements in combination chemotherapy regimens, the overall survival has increased to over 90%. However, the current challenge is to mitigate adverse events resulting from the c...

2021-08-12 | MTBLS2394 | MetaboLights
TranscriptomicsRNA-Seq of synovial tissue biopsies from individuals with rheumatoid arthritis from the R4RA randomised clinical trial
Transcriptomic profiles of synovial biopsies of rheumatoid arthritis (RA) patients who were recruited into the R4RA randomised clinical trial. Patients were randomised to treatment with rituximab or tocilizumab. All patients fulfilled the 2010 ACR/EULAR classification criteria for RA and were eligib...
ORGANISM(S): Homo sapiens 
2022-04-26 | E-MTAB-11611 | biostudies-arrayexpress
TranscriptomicsRNA-seq of synovial biopsies from rheumatoid arthritis patients
Synovial biopsies from rheumatoid arthritis patients were obtained and profiled using RNA-seq. Patients were stratified according to the number of swollen joints they had (SJC, swollen joint count) and divided in three groups for the differential expression analysis: None (SJC = 0), Low (1<= SJC <= ...
ORGANISM(S): Homo sapiens 
2021-04-26 | E-MTAB-6684 | biostudies-arrayexpress
TranscriptomicsEarly disruption of maternal-zygotic interaction and activation of defense-like responses in Arabidopsis interspecific incompatibility
Hybridization of diverged taxa often result in lethality or sterility. We previously described natural variation for postzygotic incompatibility in the cross of diploid Arabidopsis thaliana to Arabidopsis arenosa. Hybrid seed death in this system has a complex genetic basis, involving many non-addit...
ORGANISM(S): Arabidopsis thaliana 
2013-06-05 | E-GEOD-42957 | biostudies-arrayexpress
TranscriptomicsPatterns of gene expression associated with recovery and injury in heat-stressed rats
Background: The in vivo gene response associated with hyperthermia and subsequent return to homeostasis or development of heat illness is poorly understood. Early activation of gene networks in the heat stress response is likely to lead to the systemic inflammation, multi-organ functional impairment...
ORGANISM(S): Rattus norvegicus 
2015-01-14 | E-GEOD-56740 | biostudies-arrayexpress
UnknownDung removal increases under higher dung beetle functional diversity regardless of grazing intensification.
Not available
S-EPMC10700315 | biostudies-literature
UnknownWhen the wild things are: Defining mammalian diel activity and plasticity.
Not available
S-EPMC11864191 | biostudies-literature
UnknownVariation in Early Management Practices in Moderate-to-Severe ARDS in the United States: The Severe ARDS: Generating Evidence Study.
Not available
S-EPMC8176896 | biostudies-literature
UnknownWhole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.
Not available
S-EPMC11600029 | biostudies-literature
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