Lewis acid - OmicsDI

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Unknown (2527)
Transcriptomics (404)
Proteomics (186)
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Mus musculus (141)
Homo sapiens (118)
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Caenorhabditis elegans (32)
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Ferroglobus placidus DSM 10642 (8)
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Shewanella oneidensis MR-1 (2)
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Rhodopseudomonas palustris (1)
environmental samples (1)

Organisms

Homo sapiens (4)
Caulobacter vibrioides (1)
Escherichia coli str. K-12 substr. MG1655 (1)
Zea mays (1)
Arabidopsis thaliana (1)
Rattus norvegicus (1)
Mus musculus (1)

Repository

biostudies-arrayexpress (435)
pride (156)
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Tissue

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Disease

Breast cancer (5)
Disease free (5)
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Not Available (2)
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Bacterial sepsis (1)
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COVID-19 (1)
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Head and neck squamous cell carcinoma (1)
Kidney cancer (1)
Lung cancer (1)
Mitochondrial metabolism disease (1)
Nemaline myopathy (1)
Oculocutaneous albinism type VII (1)
Parkinson's disease (1)
Periodontitis (1)
Rheumatoid arthritis (1)

Technology Type

Mass Spectrometry (158)
Shotgun proteomics (86)
Mass spectrometry (41)
Bottom-up proteomics (36)
NMR spectroscopy (17)
Data-dependent acquisition (16)
Affinity purification coupled with mass spectrometry proteomics (12)
SWATH MS (11)
Gel-based experiment (7)
HDMSE (7)
Mass spectrometry assay (6)
Data-independent acquisition (5)
ESI (2)
All-ion fragmentation (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
MSE (2)
SRM/MRM (2)
Top-down proteomics (2)
Illumina HiSeq 2500 (ILLUMINA), AB SOLiD System (ABI_SOLID) (1)
NMR spectroscopy assay (1)
Glycoproteomics (1)
Sodium dodecyl sulfate polyacrylamide gel electrophoresis (1)

Instrument Platform

Liquid Chromatography MS - negative - reverse phase (17)
Liquid Chromatography MS - positive - reverse phase (13)
Illumina HiSeq 2500 (8)
Bruker (8)
Nuclear Magnetic Resonance (NMR) - (8)
Liquid Chromatography MS - positive - hilic (8)
Illumina HiSeq 4000 (7)
Q Exactive (6)
Gas Chromatography MS - positive (6)
NextSeq 500 (5)
Liquid Chromatography MS - negative - hilic (5)
Illumina NovaSeq 6000 (4)
Orbitrap Eclipse (4)
Orbitrap Fusion Lumos (4)
LTQ Orbitrap Velos (3)
Beadarray reader (2)
Illumina HiSeq 2000 (2)
Instrument (2)
Orbitrap Fusion (2)
Q Exactive Plus (2)
UC Irvine HPC (1)
Bioanalyzer, Nanodrop, (1)
GeneChip Scanner 2500 (1)
Affymetrix Gene Titan (1)
Gene Titan (1)
Illumina HiSeq 1500 (1)
LTQ Orbitrap Elite (1)
MicrOTOF-Q II (1)
Orbitrap Exploris 480 (1)
Q Exactive HF (1)

Publication Date

2011 (70)
2010 (55)
2025 (47)
2016 (43)
2012 (42)
2014 (41)
2020 (38)
2024 (37)
2015 (37)
2023 (36)
2022 (35)
2013 (35)
2021 (30)
2008 (29)
2009 (28)
2026 (21)
2019 (21)
2018 (16)
2007 (16)
2017 (8)
2005 (7)
2006 (5)
2002 (1)

UNIPROT ID/AC

6PGD_ECOLI (1)
6PGL_ECOLI (1)
A2MG_ECOLI (1)
AAEB_ECOLI (1)
AAT_ECOLI (1)
ACCA_ECOLI (1)
ACCC_ECOLI (1)
ACCD_ECOLI (1)
ACEA_ECOLI (1)
ACKA_ECOLI (1)
ACNA_ECOLI (1)
ACNB_ECOLI (1)
ACP_ECOLI (1)
ACRA_ECOLI (1)
ACRE_ECOLI (1)
ACSA_ECOLI (1)
ACUI_ECOLI (1)
ADHE_ECOLI (1)
AEGA_ECOLI (1)
AGP_ECOLI (1)
AHPC_ECOLI (1)
AHPF_ECOLI (1)
AHR_ECOLI (1)
AK1H_ECOLI (1)
AK2H_ECOLI (1)
AK3_ECOLI (1)
ALDA_ECOLI (1)
ALF1_ECOLI (1)
ALF_ECOLI (1)
ALKH_ECOLI (1)

CHEBI ID

CHEBI:86038 (13)
CHEBI:77537 (13)
CHEBI:84650 (13)
CHEBI:78811 (13)
CHEBI:76291 (13)
CHEBI:77547 (13)
CHEBI:84061 (13)
CHEBI:29140 (13)
CHEBI:85640 (13)
CHEBI:51824 (13)
CHEBI:77202 (13)
CHEBI:77228 (13)
CHEBI:74084 (13)
CHEBI:74087 (13)
CHEBI:74128 (13)
CHEBI:76368 (13)
CHEBI:73028 (13)
CHEBI:73870 (13)
CHEBI:73856 (13)
CHEBI:74086 (13)
CHEBI:74296 (13)
CHEBI:63419 (13)
CHEBI:28868 (13)
CHEBI:71687 (13)
CHEBI:31528 (13)
CHEBI:89742 (13)
CHEBI:73066 (13)
CHEBI:73072 (13)
CHEBI:84634 (13)
CHEBI:74265 (13)

Metabolite Name

Creatine (11)
Alanine (10)
Creatinine (10)
Hypoxanthine (10)
Leucine (9)
Phenylalanine (9)
Glycine (8)
Alanine (8)
Valine (8)
Leucine (8)
Valine (8)
Choline (8)
Tyrosine (8)
Linoleic acid (8)
Glutamine (8)
Uridine (8)
Serine (7)
Proline (7)
Phenylalanine (7)
Isoleucine (7)
Taurine (7)
Lysine (7)
Proline (7)
Adenine (7)
Uric acid (7)
Acetate (6)
Tryptophan (6)
Lysine (6)
Tyrosine (6)
Methionine (6)

First Public Date

2025 (3)
2014 (3)
2026 (2)
2021 (1)
2019 (1)
2017 (1)

Modelling Approach

Constraint-based model (14)
Ordinary differential equation model (1)

Lab affiliation

Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne 3000, Australia (15)
Department of Microbiology and Immunology, The University of Melbourne, Victoria, Australia (10)
Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for infection and immunity, Melbourne, 3000, Australia (10)
Cornell University Department of Microbiology (3)
Division of Genetic and Genomic Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, USA (3)
Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics, Princeton University, USA (3)
Department of Biological Sciences, University of Arkansas, Fayetteville, Arkansas, United States of America (2)
Department of Microbial Physiology and Molecular Biology, Institute of Microbiology, University of Greifswald (2)
Department of Molecular Biology & the Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA (2)
Faculty of Chemistry, Biotechnology and Food Science Norwegian University of Life Sciences Post Office Box 5003 1432, Ås Norway (2)
School of Biochemistry, Biomedical Sciences Building, University Walk, University of Bristol, BS8 1TD, U.K. (2)
University of Bristol (2)
University of Copenhagen Department of Biomedical Sciences Blegdamsvej 3B København N, DK-2200 (2)
University of Manchester (2)
Wuhr Lab, Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics, Princeton University, USA (2)
1Department of Microbiology, University of Washington, Seattle, Washington, USA (1)
Aging and Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA (1)
Analytical Biochemistry and Proteomics Unit (1)
Associate Professor, Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, USA (1)
Associate Professor, Dept. Biochemistry, Memorial University of Newfoundland, Canada (1)
Associate Professor, School of Biological Sciences, University of Southampton (1)
Associate professor, School of Biosciences, University of Southampton, England (1)
BU Bioscience, Wageningen Plant Research, Wageningen UR. the Netherlands (1)
Breast Center - Lewis, Baylor College of Medicine, Houston TX US (1)
CIR, Queen’s Medical Research Institute, University of Edinburgh (1)
Center for Metabolic Disease Research (CMDR) Lewis Katz School of Medicine at Temple University Medical Education and Research Building, Room 1060 3500 N. Broad Street Philadelphia, PA 19140, USA (1)
Centre for Cancer Biology, SA Pathology and the University of South Australia, Adelaide SA 5000, Australia (1)
Chemical & Biomolecular Engineering, Johns Hopkins University (1)
Chemistry Department, University of California, Davis, USA (1)
Chemistry and Biochemistry, University of Windsor, Canada (1)

IsPrivate

False (15)

Submitter Keywords

FROG (1)

Classification

bacteria (1)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study type

Transcription profiling by array (293)
RNA-seq of coding RNA (43)
ChIP-seq (31)
Unknown experiment type (13)
Methylation profiling by array (9)
Comparative genomic hybridization by array (8)
RNA-seq of non coding RNA (7)
Other (5)
Transcription profiling by tiling array (4)
RNA-seq of coding RNA from single cells (4)
RNA-seq of total RNA (4)
Genotyping by array (3)
Baseline (2)
Animal - High-throughput sequencing (2)
Proteomic profiling by array (2)
Methylation profiling by high throughput sequencing (2)
ChIP-chip by tiling array (1)
MicroRNA profiling by high throughput sequencing (1)
RIP-seq (1)

Release Date

2022 (266)
2023 (250)
2021 (246)
2025 (236)
2024 (209)
2020 (197)
2018 (174)
2019 (166)
2016 (149)
2015 (132)
2011 (132)
2014 (128)
2017 (124)
2010 (106)
2013 (88)
2012 (88)
2009 (65)
2008 (57)
2026 (47)
2007 (39)
2006 (21)
2005 (18)
2004 (8)
2002 (4)
2000 (4)
1998 (3)
2003 (2)
2001 (1)
1999 (1)
1997 (1)

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Untargeted gas chromatography–mass spectrometry-based metabolomics analysis of kidney and liver tissue from the Lewis Polycystic Kidney rat

Polycystic kidney disease (PKD) encompasses a spectrum of inherited disorders that lead to end-stage renal disease (ESRD). There is no cure for PKD and current treatment options are limited to renal replacement therapy and transplantation. A better understanding of the pathobiology of PKD is needed ...

2023-01-26 | MTBLS748 | MetaboLights

Lewis lung carcinoma cells and TDAG8 overexpression

We observed the effects of TDAG8-overexpression in Lewis lung carcinoma (LLC) cells on the gene expression pattern. TDAG8-overexpressing or vector-transfected control LLC cells (5 × e5 in 200 µL of HBSS) were injected into the lateral tail veins of 6–8-week-old C57BL/6 mice. Lungs were removed on da...

ORGANISM(S): Mus musculus

2010-09-06 | E-GEOD-18244 | biostudies-arrayexpress

Evidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights

miRNA expression in myeloid-derived suppressor cells (MDSCs) treated with or without whole ?-glucan particles (WGP)

Murine MDSCs isolated from the spleens of Lewis lung carcinoma mice were treated with or without WGP, and then miRNA array was used to analyze the differentailly expressed miRNAs. Murine MDSCs were isolated from the spleens of Lewis lung carcinoma tumor-bearing mice, and the sorted MDSCs were stimul...

ORGANISM(S): Mus musculus

2015-06-26 | E-GEOD-67578 | biostudies-arrayexpress

RNA-seq of muscle in mice with Lewis lung carcinoma with or without access to physical activity

Exercise has been correlated with prevention of weight loss (cachexia) attributed to tumor initiation and progression. However, it is unclear what are the molecular mechanisms behind this beneficial effect of exercise to prevent cachexia. In this study, we obtained RNA-seq data from biopsies of musc...

ORGANISM(S): Mus musculus

2019-08-14 | E-MTAB-5974 | biostudies-arrayexpress

Gene Expression Changes in the Spinal Cords of Lewis Rats with Myelin Basic Protein-Induced Experimental Autoimmune Encephalomyelitis (EAE)

Myelin Basic Protein (MBP) induced experimental autoimmune encephalomyelitis (EAE) in the Lewis rat, produces an an acute weakness, or paralysis of the tail and hind limb ataxia ,weakness or paralysis associated with increased permiability of the blood brain barrier, inflammation and demyelination i...

ORGANISM(S): Rattus norvegicus

2013-04-03 | E-GEOD-39119 | biostudies-arrayexpress

Transcriptomic profile of Sialyl-Lewis X (CD15s)+ basophils and Sialyl Lewis X- basophils

PRJNA504452 | ENA

Transcription profiling of rat heart from Lewis strain immunized with a peptide of human alpha1A-adrenergic receptor

Gene expression profiles in hearts of Lewis rats immunized with a peptide of human alpha1A-adrenergic receptor. The pathophysiological relevance of chronic autoantibodies against alpha-1A-adrenergic receptor stimulation in rats was investigated. Lewis rats were immunized using synthesized peptides o...

ORGANISM(S): Rattus norvegicus

2010-06-15 | E-TABM-725 | biostudies-arrayexpress

Whole transcriptome of Lewis lung carcinoma cells of Mus musculus

Purpose: To study the alteration of whole transcriptome of Lewis lung carcinoma (LLC) cells after the decreasing of malignant properties of tumor by treatment of tumor-bearing mice with RNase A. Methods: Whole transcriptome profile of Lewis lung carcinoma before and after RNase A treatment were gene...

ORGANISM(S): Mus musculus

2014-12-03 | E-GEOD-63758 | biostudies-arrayexpress

Transcription profiling of mammary glands from virgin or parous Lewis strain rats

Independent Lewis rat data used to confirm the finding of the main experiment "Protection against Mammary Tumorigenesis in Multiple Rat Strains (experiment E-TABM-197: https://www.ebi.ac.uk/arrayexpress/experiments/E-TABM-197).

ORGANISM(S): Rattus norvegicus

2007-01-31 | E-TABM-198 | biostudies-arrayexpress

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