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MetabolomicsPlasma sphingolipid changes with autopsy-confirmed Lewy body or Alzheimer's pathology
Not available
ORGANISM(S): Homo sapiens 
ST000433 | MetabolomicsWorkbench
ProteomicsThe proteome of neuromelanin granules in dementia with Lewy bodies
Neuromelanin granules (NMGs) are organelle-like structures present in the human substantia nigra pars compacta. Besides neuromelanin, NMGs contain proteins, lipids and metals. As NMG-containing dopaminergic neurons are preferentially lost in Parkinson’s disease and dementia with Lewy bodies (DLB), i...
ORGANISM(S): Homo sapiens (Human) 
2023-02-14 | PXD035310 | Pride
Proteomics Stress granules Substantia nigra pars compacta Dementia with lewy bodies Neurodegeneration Neuromelanin granules 
ProteomicsOlfactory proteomics in Dementia with Lewy bodies
Proteomic analysis were performed in olfactory bulbs derived from controls and individuals with dementia with lewy bodies
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD016069 | Pride
Brain Proteomics Olfactory bulb 
ProteomicsThe Parkinson's disease protein alpha-synuclein is a direct modulator of Processing-bodies and mRNA stability
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, Udeshi ND, Mani DR,Carr SA, de Jager P, Myers CL, Lindquist S, Greenmyre TJ, Bartel DP, Feany MB, Sunyaev S, Chung CY and Khurana V. Alp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-09 | MSV000089026 | MassIVE
UnknownResearch priorities of caregivers and individuals with dementia with Lewy bodies: An interview study.
Not available
S-EPMC7540843 | biostudies-literature
TranscriptomicsA Study of Small RNAs from Cerebral Neocortex of Pathology-Verified Alzheimer’s Disease, Dementia with Lewy Bodies, Hippocampal Sclerosis, Frontotemporal Lobar Dementia, and Non-Demented Human Controls
MicroRNAs (miRNAs) are small (20-22 nucleotides) regulatory non-coding RNAs that strongly influence gene expression. Most prior studies addressing the role of miRNAs in neurodegenerative diseases (NDs) have focused on individual controls (n = 2), AD (n = 5), dementia with Lewy bodies (n = 4), hippoc...
ORGANISM(S): Homo sapiens 
2013-04-18 | E-GEOD-46131 | biostudies-arrayexpress
UnknownPlasma phosphorylated tau and neuropsychiatric symptoms in dementia with Lewy bodies.
Not available
S-EPMC11848415 | biostudies-literature
UnknownImplications and opportunities regarding biological frameworks in overt and prodromal dementia with Lewy bodies.
Not available
S-EPMC12276075 | biostudies-literature
ProteomicsProteomic Profiling of the Substantia Nigra to Identify Determinants of Lewy Body Pathology and Dopaminergic Neuronal Loss
Proteinaceous aggregates containing alpha-synuclein protein called Lewy bodies in the substantia nigra is a hallmark of Parkinson's disease. The molecular mechanisms of Lewy body formation and associated neuronal loss remain largely unknown. To gain insights on proteins and pathways associated with ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD019279 | Pride
Brain Lewy bodies Substantia nigra Lc-ms/ms 
UnknownNeuropsychological test performance in mild cognitive impairment with Lewy bodies: A systematic review and meta-analysis.
Not available
S-EPMC11848198 | biostudies-literature
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