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This data included proteomic data of 57 Alzheimer's disease patients, 43 mild cognitive patients and 62 cognitively normal controls.
ORGANISM(S): Homo Sapiens 
2023-08-18 | PXD044672 |
Recently, we presented the DirectMS1 method of ultrafast proteome-wide analysis based on minute-long LC gradients and MS1-only mass spectra acquisition. Currently, the method provides the depth of human cell proteome coverage of 2500 proteins at 1% false discovery rate (FDR) when using 5-min LC grad...
ORGANISM(S): Homo sapiens (Human) 
2023-08-25 | PXD033355 | Pride
Venous blood was collected in Li-heparin or EDTA blood tubes and loaded onto 20 uL Mitra devices or separated to plasma as detailed in metadata. Samples were denatured in 5.5% SDC, reduced and alkylated, and digested with TPCK-trypsin followed by acid precipitation. 1 mg of filtered precipitates wer...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-10 | MSV000093624 | MassIVE
After cell lysis, the global proteomes of wild-type 786O and OTUD3-knockdown (KD) 786O cell lines were analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Label-free quantification (LFQ) was employed for comparative protein quantification, and tandem mass spectrometry data were...
ORGANISM(S): Homo sapiens (Human) 
2025-08-15 | PXD064004 | Pride
The Dynamic Organellar Maps (DOMs) approach combines cell fractionation and shotgun-proteomics for global profiling analysis of protein subcellular localization. Here, we have drastically enhanced the performance of DOMs through data-independent acquisition (DIA) mass spectrometry (MS). DIA-DOMs ach...
ORGANISM(S): Homo sapiens (Human) 
2023-08-25 | PXD034962 | Pride
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