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ProteomicsNew insight into sclerotial generation in medicinal fungus Polyporus umbellatus
Polyporus umbellatus sclerotia are medicinal tissue, but little is known about acetylome of sclerotia generated from hyphae. Based on acetylome analysis results and expression levels of targeted protein that associated with sclerotia generation were verified by PRM using Orbitrap Fusion (Thermo-Fish...
ORGANISM(S): Polyporus umbellatus GSX09 
2022-05-20 | PXD031198 | Pride
Polyporus umbellatus Ultimate3000 rslc nano 
ProteomicsAcetylome analysis of acetylation providing new insight into sclerotial generation in medicinal fungus Polyporus umbellatus
Polyporus umbellatus sclerotia are medicinal tissue, but little is known about acetylome of sclerotia generated from hyphae. Acetylated peptides in P. umbellatus were enriched by anti-acetyl-lysine antibody beaded agarose and DDA data were acquired by AB Triple TOF 5600+. Raw data were analyzed by P...
ORGANISM(S): Polyporus umbellatus GSX09 
2022-05-20 | PXD031195 | Pride
Ab triple tof5600+ Polyporus umbellatus 
TranscriptomicsGenomic encoding of transcriptional burst kinetics
We used single-cell RNA-sequencing to generate allele-resolution expression levels in individual cells that we used for inference of transcriptional burst kinetics.
ORGANISM(S): Mus musculus 
2018-09-30 | E-MTAB-6362 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of wild type, SET2 deletion, Rco1 PHD domain deletion and Eaf3 chromodomain deletion yeast using anti-acetyl-histone H4
Nucleosomes must be deacetylated behind elongating RNA polymerase II to prevent cryptic initiation of transcription within the coding region. RNA polymerase II signals for deacetylation through methylation of histone H3 lysine 36 (H3K36) which provides the recruitment signal for the Rpd3S deacetylas...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-16 | E-TABM-260 | biostudies-arrayexpress
ModelsLiu1999_PulsatileSecretion
This a model from the article: A dynamical model for the pubsatile secretion of the hypothalamo-pituitary-adrenal axis. Yi-wei Liu, Zhi-Hong Hu, Jian-Hua Peng and Bing-Zheng Liu Mathematical and Computer Modelling Volume 29, Issue 4, February 1999, Pag...
2005-01-01 | MODEL1006230060 | BioModels
TranscriptomicsTranslation initiation at a non-AUG start codon for mouse and human NELF-B
Negative elongation factor (NELF), a four-subunit protein complex in metazoan, plays an important role in regulating promoter-proximal pausing of RNA polymerase II (RNAPII). Genetic studies demonstrate that the B subunit of mouse NELF (NELF-B) is critical for embryonic development and homeostasis i...
ORGANISM(S): Mus musculus 
2014-10-11 | E-GEOD-62248 | biostudies-arrayexpress
UnknownChiglitazar diminishes the warburg effect through PPARγ/mTOR/PKM2 and increases the sensitivity of imatinib in chronic myeloid leukemia.
Not available
S-EPMC11657277 | biostudies-literature
MetabolomicsSacha inchi oil alleviates gut microbiota dysbiosis and improves hepatic lipid dysmetabolism in high-fat diet-fed rats
Dietary ω-3 polyunsaturated fatty acids (PUFAs) are beneficial for humans against the development of hyperlipidaemia, but the underlying mechanisms are still poorly understood. Here, we demonstrated that oral consumption of sacha inchi oil, which is rich in α-linolenic acid, alleviated dyslipidemia,...
2022-02-21 | MTBLS1225 | MetaboLights
UnknownLow G preconditioning reduces liver injury induced by high +Gz exposure in rats.
Not available
S-EPMC4458764 | biostudies-literature
TranscriptomicsHeart tissue from Nelf-b CreER mice
Negative elongation factor (NELF) is known to enforce promoter-proximal pausing of RNA polymerase II (Pol II), a pervasive phenomenon observed across multicellular genomes. However, the physiological impact of NELF on tissue homeostasis remains unclear. Here we show for the first time that whole-b...
ORGANISM(S): Mus musculus 
2014-03-01 | E-GEOD-54372 | biostudies-arrayexpress
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