To reveal the direct target and molecular mechanisms underlying the effects of dezocine, a pull-down assay and HPLC-MS/MS were performed.l the direct target and molecular mechanisms underlying the effects of dezocine, a pull-down assay and HPLC-MS/MS were performed.
In order to detect the effect of Dasabuvir on the protein expression of esophageal cancer cells, we used control and drug-added KYSE150 cells for proteomic analysis
Understanding of the molecular regulatory mechanisms underlying the inflammatory response isincomplete, especially with respect to the global proteomic response to microbial infection. Data-independent acquisition (DIA)-based quantitative proteomic analysis has been widely applied inproteomics resea...
Bovine milk-derived exosomes (BMDEs) have potential applications in the pharmaceutical industry as drug delivery carriers. A comprehensive analysis of protein glycosylation in exosomes is necessary to elucidate the process of target delivery. In this work, free oligosaccharides (FOSs), O-glycans and...
Our study describes the landscape of the molecular dynamics of serum exosomes during the development of sepsis and proposes some hypothetical molecular mechanisms, which may provide helpful diagnostic and therapeutic insights for the ongoing battle against sepsis.
