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Over-expression of Stat3C in lung alveolar type II epithelial cells of CCSP-rtTA/(teto)7Stat3C bitransgenic mice leads to severe pulmonary inflammation in the lung. As a consequence, spontaneous lung bronchoalveolar adenocarcinoma was observed in bitransgenic mice. Aberrantly expressed genes in th...
ORGANISM(S): Mus musculus 
Mutations of RUNX1 are detected in patients with myelodysplastic syndrome (MDS). In particular, C-terminal truncation mutations lack a transcription regulatory domain and have increased DNA binding through the runt homology domain (RHD). The expression of the RHD, RUNX1(41-214), in mouse hematopoiet...
ORGANISM(S): Mus musculus 
Using CXMS to probe the effect of persulfidation on AtG6PD6 homooligomer structure. Abundant cross-links were identified within both AtG6PD6 monomer and oligomer (Datasets S2 and 3). Based on the cross-linking information, models of the AtG6PD6 dimer and tetramer structures were constructed.
ORGANISM(S): Arabidopsis Thaliana 
2023-07-20 | PXD043969 |
Erhualian (EHL) is one of the seven strains included in a Chinese indigenous pig breed called Taihu. EHL is famous for its early sexual maturity, large litter size, high adiposity, mild temper, good maternity and high tolerance to roughage and stress. To further investigate the role of miRNAs in dif...
ORGANISM(S): Sus scrofa 
To reveal the risk CNVs of SZ in Chinese population, we recrited and enrolled 100 Chinese family trios with a schizophrenia affected children and both of their father and mother. SZ was diagnosed according to DSM-IV criteria by two independent psychiatrists. There gDNA we screen the genome-wide CNV...
ORGANISM(S): Homo sapiens 
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