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UnknownBlood pressure variability combined with coagulation function in early prediction and outcome assessment of germinal matrix-intraventricular hemorrhage in preterm infants with gestational age ≤32 weeks
Not available
S-EPMC12289036 | biostudies-literature
UnknownCRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules.
Not available
S-EPMC8179559 | biostudies-literature
UnknownThe liver-specific long noncoding RNA FAM99B inhibits ribosome biogenesis and cancer progression through cleavage of dead-box Helicase 21.
Not available
S-EPMC11829061 | biostudies-literature
ProteomicsIsonicotinylation is Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazida histone mark induced by the anti-tuberculosis first-line drug isoniazid
Isoniazid (INH) is the first-line anti-tuberculosis drug used for nearly seventy years. Metabolites of INH showed hepatotoxicity in human and tumorigenicity in rodents. However, mechanism underlying the side effects of INH is elusive. Histone acylation is known to be modulated by intracellular metab...
ORGANISM(S): Homo sapiens (Human) 
2021-08-20 | PXD025490 | Pride
Histone isonicotinyltransferases Histone deisonicotinylases Gene transcription Histone isonicotinylation Chromatin structure 
ProteomicsQuantitative Proteome of Infant Stenotic Ureters Reveals Extracellular Matrix Organization and Oxidative Stress Dysregulation Underlying Ureteropelvic Junction Obstruction
Ureteropelvic junction obstruction (UPJO) is the most frequent cause of congenital hydronephrosis in child. To better investigate the molecular mechanisms of this pathological process, we performed data independent acquisition-based proteomics to compare the stenotic ureter proteome of UPJO in infan...
ORGANISM(S): Homo Sapiens 
2020-08-17 | PXD020116 |
ProteomicsMass spectrometry proteomics detecting interaction proteins of Kindlin-2
We aim to find out the Kindlin-2 interaction proteins. We transfected plasmids Flag or Flag-Kindlin-2 to HKC cell lines and then used Flag-M2 beads to do the coimmunoprecipitation experiments and followed by NuPAGE Tris-Acetate Mini Gels detection and stained by Coomassie brilliant blue. Compared th...
ORGANISM(S): Homo sapiens (Human) 
2019-12-16 | PXD016008 | Pride
Human renal tubular epithelial cell(hkc) 
ProteomicsProteomic analysis of the antimicrobial effects of sublethal concentrations of thymol on S. Typhimurium
In a quantitative proteomic assay, sequential window acquisition of all theoretical spectra (SWATH) combined with 2D LC MS/MS is emerging as a powerful methodology in the search for disease specific targets and biomarkers using cell lines, tissues, body fluids and so on.
ORGANISM(S): Salmonella Enterica Subsp. Enterica Serovar Typhimurium 
2019-08-31 | PXD015263 |
ProteomicsDDX5-sIL-36R in keratinocytes controls skin inflammation
The DEAD-box (DDX) proteins function in diverse cellular processes including RNA alternative splicing, and are linked to immune-mediated diseases. However, little is known about the roles of DDXs in skin inflammatory diseases. Here, we show that DDX5, one of the founding members of the DDX RNA helic...
ORGANISM(S): Homo Sapiens 
2020-09-09 | PXD021379 |
ProteomicsCRISPR screening reveals that RNA helicase DDX41 triggers ribosome biogenesis and cancer progression through R-loop-mediated RPL/RPS transcription
The RNA helicase DDX41 is a DEAD-box helicase that is well known as a virus sensor in dendritic cells and a tumor suppressor that is frequently mutated in myeloid neoplasms. However, the functions and relevance of DDX41 in solid tumors remain largely unexplored. In this study, through in vivo CRISPR...
ORGANISM(S): Homo Sapiens 
2024-12-23 | PXD059178 |
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