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ProteomicsProteome analysis of the hemolymph, mushroom body, and antenna of honeybee resistance against Varroa infestation
As a matter of fact, honeybees are vital for the pollination of more than 80 crops of agricultural interest. However, population decline has become an important global issue causing significant concerns among agricultural experts and the broader public. For this, parasites are known to be the major ...
ORGANISM(S): Apis mellifera (Honeybee) 
2016-08-09 | PXD004467 | Pride
Apis mellifera Antennae Hemolymph Varroa sensitive hygiene Mushroom body Varroa destructor 
Proteomicshoneybee brain - Brain Membrane Proteome and Phosphoproteome Reveal Molecular Basis Associating with Nursing and Foraging Behaviors of Honeybee Workers
he brain is a vital organ in regulating complex social behaviors of honeybees including learning and memory. Knowledge of how brain membrane proteins and their phosphorylation underlie the age-related behavioral polyethism is still lacking. We presented the first comprehensive profiling and comparis...
ORGANISM(S): Apis mellifera (Honeybee) 
2017-09-11 | PXD006823 | Pride
Membrane Brain Honeybee Proteome Phosphoproteome 
ProteomicsApis mellifera,Hemolymph,LC-MSMS
We characterized and compared hemolymph proteome of Royal Jelly bees (RJbs), a stock selected for increasing RJ output from Italian bees (ITbs) and ITbs across the larval and adult ages. Unprecedented depth of proteome was attained by identifying 3394 hemolymph proteins in both bee lines. The proteo...
ORGANISM(S): Apis mellifera (Honeybee) 
2017-11-30 | PXD007824 | Pride
Royal jelly bees Hemolymph Proteome Italian bees 
ProteomicsHoneybee Brain LC-MS/MS - Proteomics Reveals the Molecular Underpinnings of Stronger Learning and Memory in Eastern Compared to Western Beess
Honeybee brain has distHoneybee brain has distinct anatomical and functional regions, knowledge on molecular underpinnings of sub-organ to achieve the distinct neural function and the difference between the eastern and western honeybees are still missing. Here, the proteomes of three sub-organs of e...
ORGANISM(S): Apis mellifera (Honeybee) 
2017-12-04 | PXD007091 | Pride
Honeybee mushroom bodies antennal lobes optical lobes proteome 
ProteomicsMouse VSMC LC-MSMS - Functional and Proteomic Investigations Reveal Major Royal Jelly Protein 1 Associated with Anti-hypertension Activity in Mouse Vascular Smooth Muscle Cells
Vascular smooth muscle cells (VSMCs) are a major cell type of the arterial wall and their functionality is associated with blood pressure regulation. Although royal jelly (RJ) has reported effects on anti-hypertension, the mechanism of blood pressure regulation by major royal jelly protein 1 (MRJP1)...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-27 | PXD004207 | Pride
Mouse Vsmc Mrjp1 Lc-msms 
ProteomicsHoneybee hypopharyngeal glands LC-MS/MS
Royal jelly (RJ) is a proteinaceous secretion of the hypopharyngeal glands (HGs) in the head of honeybee workers. It is a critical food for queen bees and young larvae that decides the fate of fertilized eggs in developing into either queen bees or worker bees during the early larval stages. RJ is a...
ORGANISM(S): Apis mellifera (Honeybee) 
2019-01-11 | PXD010898 | Pride
Honeybee Hypopharyngeal glands High royal jelly producing bees 
ProteomicsDeep Phosphoproteome Analysis Reveals Neurobiological Underpinnings for Nurse and Forager Honeybee Workers (Apis mellifera ligustica)
The honeybee brain is comprised of a nervous system that sufficiently regulates this life transition. Knowledge about how protein phosphorylation functions in regards to the neurobiological activities in the honeybee brain to drive the age-specific labor division is still lacking. Protein phosphoryl...
ORGANISM(S): Apis mellifera (Honeybee) 
2018-10-26 | PXD003757 | Pride
Brain Phosphoproteome Nurses Worker Foragers Honeybee 
ProteomicsPhosphorylation Regulatory Networks during honeybee embryogenesis
Protein phosphorylation is known to regulate a wide scenario of key cellular processes. However, phosphorylation mediated regulatory networks in honeybee embryogenesis are largely unknown. We identified 6342 phosphosites from 2438 phosphoproteins and predicted 168 kinases in the honeybee embryo. The...
ORGANISM(S): Apis Mellifera 
2022-04-19 | PXD033311 |
Proteomics10-HDA reduces the hydroxyl free radical-induced damage to vascular smooth muscle cells by rescuing protein and energy metabolisms
10-hydroxydec-2-enoic acid (10-HDA), a natural agent from royal jelly, could fight against cell and tissue damage, yet the underlying mechanisms are still unexplored. Here, we found the scavenging rate of hydroxyl free radical (•OH) by 2% (g/mL) 10-HDA was more than 20%, which was achieved by a mult...
ORGANISM(S): Mus Musculus 
2021-11-22 | PXD029873 |
ProteomicsHoneybee queen ovary proteomics
Using honey bee (Apis mellifera) as a model, we confirmed that honeybee queens with big ovaries lay smaller eggs in colonies with more worker bees.
ORGANISM(S): Apis Mellifera 
2021-11-22 | PXD029859 |
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