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ProteomicsU2OS osteosarcoma cells LC-MSMS
In order to identify the targets of miR-193a-5p in osteosarcoma U2OS cell line, we used a lentivirus-mediated expression system to overexpressing miR-193a precusor, miR-193a-5p target sequence and non-target sequence, respectively, in osteosarcoma cell line U2OS. A tandem mass tag (TMT)-based quanti...
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD013987 | Pride
Lc-msms Osteosarcoma U2os Mir-193a-5p 
ProteomicsIdentification of novel serum biomarkers for malignant mesothelioma using iTRAQ combined with 2D-LC-MS/MS
In this project, differential serum proteins (DEPs) were first screened in MM patients and healthy controls using iTRAQ labeling coupled with 2D LC-MS/MS method. As a result, 475 proteins were identified, of which, 327 proteins contain at least two unique peptides, and 145 DEPs were found between M...
ORGANISM(S): Homo Sapiens 
2019-10-30 | PXD016073 |
ProteomicsIntegrated microRNA and secretome analysis of human endometrial organoid reveal the miR-3194-5p/Aquaporin/S100A9 module in regulating trophoblast functions
Successful placentation requires delicate communication between endometrium and trophoblasts. The invasion and integration of trophoblasts into the endometrium during early pregnancy is crucial to placentation. Dysregulation of these functions is associated with various pregnancy complications such ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD036535 | Pride
Secretome  human endometrial organoid  itraq  lc-ms/ms 
ProteomicsMTH1's role in platelet function
MTH1 knockout mice were utilized to evaluate its role in platelet mitochondrial function and thrombosis
ORGANISM(S): Mus Musculus 
2023-04-14 | PXD041528 |
ProteomicsPeptide codes for organ-selective mRNA delivery
Organ-selective delivery of messenger RNA (mRNA) is critical for fulfilling the therapeutic potential of mRNA-based gene and protein replacement technologies. Despite clinical advances in hepatic delivery of mRNA using lipid nanoparticles (LNPs), strategies for extrahepatic organ-selective mRNA deli...
ORGANISM(S): Mus Musculus 
2023-07-20 | PXD043932 |
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