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GenomicsWickerhamiella versatilis
Wickerhamiella versatilis Transcriptome or Gene expression
PRJNA813011 | ENA
GenomicsRegulation of Mammalian Cell Growth and Survival By an RNA Polymerase II-Pausing Factor (ChIP-seq)
Many mammalian genes are occupied by paused RNA polymerase II (pol II) at promoter-proximal regions on both sides of transcription start sites (TSSs). However, the consequences of pol II pausing on gene expression and cell biology are not fully understood. Here we report that genetic ablation of t...
ORGANISM(S): Mus musculus 
2011-08-17 | E-GEOD-24113 | biostudies-arrayexpress
UnknownSynthesis and Application of Ion-Exchange Magnetic Microspheres for Deep Removal of Trace Acetic Acid from DMAC Waste Liquid.
Not available
S-EPMC9918990 | biostudies-literature
GenomicsRegulation of Mammalian Cell Growth and Survival By an RNA Polymerase II-Pausing Factor
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2011-08-17 | E-GEOD-24180 | biostudies-arrayexpress
TranscriptomicsTex10 Coordinates Epigenetic Control of Super-Enhancer Activity for Pluripotency and Reprogramming
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-05-06 | E-GEOD-66736 | biostudies-arrayexpress
ProteomicseIF4A3 interactome by IP-MS in mouse ESCs
RNA helicases are involved in multiple steps of RNA metabolism to direct their roles in gene expression, yet their functions in pluripotency control remain largely unexplored. Starting from an RNAi screen of RNA helicases, we identified that eIF4A3, a DEAD-box (Ddx) helicase component of the exon ju...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD031362 | Pride
Ip-ms Eif4a3 Escs 
GenomicsTex10 Coordinates Epigenetic Control of Super-Enhancer Activity for Pluripotency and Reprogramming [ChIP-Seq]
Super-enhancers (SEs) are large clusters of transcriptional enhancers that are co-occupied by multiple lineage specific transcription factors driving expression of genes that define cell identity. In embryonic stem cells (ESCs), SEs are highly enriched for Oct4, Sox2, and Nanog in the enhanceosome a...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-66735 | biostudies-arrayexpress
TranscriptomicsTex10 Coordinates Epigenetic Control of Super-Enhancer Activity for Pluripotency and Reprogramming [RNA-Seq]
Super-enhancers (SEs) are large clusters of transcriptional enhancers that are co-occupied by multiple lineage specific transcription factors driving expression of genes that define cell identity. In embryonic stem cells (ESCs), SEs are highly enriched for Oct4, Sox2, and Nanog in the enhanceosome a...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-66734 | biostudies-arrayexpress
ProteomicsSILAC of hESCs with DDX18 knockdown
This study explores the crucial role of the nucleolus-specific RNA helicase DDX18 in maintaining the pluripotency of human embryonic stem cells. We demonstrate that DDX18 coordinates nucleolus phase separation and chromatin organization by interacting with NPM1 in the granular component of the nucle...
ORGANISM(S): Homo sapiens (Human) 
2024-11-18 | PXD057813 | Pride
Knockdown Ddx18 Silac 
ProteomicsTET1 interactome by SILAC IP-MS in mouse ESCs
TET1 maintains hypomethylation at bivalent promoters through its catalytic activity in embryonic stem cells (ESCs). However, whether and how TET1 exerts catalytic activity-independent functions in regulating bivalent genes is not well understood. Therefore, we mapped the TET1 interactome in mouse ES...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-10 | PXD033587 | Pride
Silac Ip-ms Tet1 Escs 
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