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Pseudomonas aeruginosa is a ubiquitous Gram-negative bacterium in the environment and a leading cause of nosocomial infections worldwide. Therefore, it is listed by the World Health Organization as one of the human pathogens that urgently need to develop new antibacterial drugs. Recent findings have...
ORGANISM(S): Pseudomonas aeruginosa PAK 
2021-07-07 | PXD027148 | Pride
After 14 days simulated microgravity,rats jejunal mucosa was taken for proteomic study. A total of 1826 proteins were detected, and 335 differentially expressed proteins were detected, of which 190 were up-regulated and 145 were down-regulated.
ORGANISM(S): Rattus Norvegicus 
Background: Candida albicans is an opportunistic pathogenic yeast, which could become pathogenic in various stressful environmental factors including the spaceflight environment. In this study,we aim to explore the phenotypic changes and possible mechanisms of Candida albicans after exposure to spac...
ORGANISM(S): Candida Albicans 
In this study, we systematically compared the proteomics identification results obtained under room temperature and high temperature.
ORGANISM(S): Homo Sapiens 
2020-01-09 | PXD017016 |
We used anti-WRN antibody to perform immunoprecipitation assay through oncosphere lysates and identified a potential interacting protein candidate
ORGANISM(S): Homo Sapiens 
We identify abnormal protein and post-translational modification (PTM) pathways, including many downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways and the reduced succinyl-CoA may lead...
ORGANISM(S): Homo Sapiens 
We identify abnormal protein and post-translational modification (PTM) pathways, including significantly downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways inextricably linked with can...
ORGANISM(S): Homo Sapiens 
We enrolled 37 SARS-CoV-2 positive patients including 17 short course (SC) COVID-19 patients (twice viral RNA detection negative over 24 hrs) and 20 COVID-19 long course (LC) COVID-19 patients. We also included 35 SARS-CoV-2 negative patients as control group. We collected 224 inactive serum samples...
ORGANISM(S): Homo Sapiens 
2022-07-26 | PXD035471 |
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