Sort   by:  
 Page size 
ProteomicsSIRT2 interactomics in HeLa cells
We aim to discovery new interactors of the deacetylase, SIRT2 from HeLa cells.
ORGANISM(S): Homo sapiens (Human) 
2023-12-05 | PXD045456 | Pride
Sirt2 
UnknownPhysicochemical and structural properties of novel cornmeal, pea protein isolate and wheat gluten meat analogues prepared by high moisture extrusion.
Not available
S-EPMC11914570 | biostudies-literature
UnknownRepurposing of HIV/HCV protease inhibitors against SARS-CoV-2 3CLpro.
Not available
S-EPMC9499987 | biostudies-literature
ProteomicsTFAM-Associated Mitochondrial Dynamics and Metabolic Reprogramming Regulate Microglial Polarization: Temporal and Causal Perspectives
The polarization state of microglia exerts an influence on neuroinflammation and neural tissue repair after injury. Modulating microglial polarization is emerging as a potential therapeutic strategy for various types of neural injuries and neurodegenerative diseases. However, the causal relationship...
ORGANISM(S): Mus Musculus 
2025-12-24 | PXD072378 |
ProteomicsAn anti-influenza A virus microbial metabolite acts by degrading viral endonuclease PA
The emergence of new highly pathogenic and drug-resistant influenza strains urges the development of novel therapeutics for influenza A virus (IAV). Here, we report the discovery of an anti-IAV microbial metabolite called APL-16-5 that was originally isolated from the plant endophytic fungus Aspergi...
ORGANISM(S): Homo sapiens (Human) 
2022-05-20 | PXD031993 | Pride
Influenza a virus  proteolysis-targeting chimeras  trim25  phenalenone derivatives  microbial metabolites  antiviral drug 
ProteomicsSARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis
The coronavirus disease 2019 (COVID-19) pandemic has devastated global health. Identifying key host factors essential for SARS-CoV-2 RNA replication is expected to unravel cellular targets for the development of broad-spectrum antiviral drugs which have been quested for the preparedness of future vi...
ORGANISM(S): Homo Sapiens 
2022-09-28 | PXD037068 |
ProteomicsProteogenomic Landscape of Breast Ductal Carcinoma Reveals Tumor Progression Characteristics and Therapeutic Targets
In this study, we performed integrated multi-omics analyses using genomic (n = 79), transcriptomic (n = 42), proteomic (n = 224), and phosphoproteomic (n = 49) data collected from 224 samples from 168 patients with malignant and benign breast diseases. Our data revealed the characteristics of the li...
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD040750 |
ProteomicsPlasma proteomic profiling discovers molecular features associated with upper urinary tract urothelial carcinoma
Upper tract urothelial carcinoma (UTUC) is often diagnosed late and exhibits poor prognosis. Only limited data are available concerning potential noninvasive biomarkers for disease monitoring. Here, we investigated the proteomic profile of plasma in 362 UTUC patients and 239 healthy control samples....
ORGANISM(S): Homo Sapiens 
2023-07-12 | PXD043774 |
Sort   by:  
 Page size