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ProteomicsRelative quantitative analysis of mouse lung tissue from bleomycin induced pulmonary lung fibrosis mice model through iTRAQ (isobaric tagging for relative and absolute quantification) quantitative proteomics
Purpose: iTRAQ performed for proteomic analysis in BLM induced mice lung tissues. The goals of this study is to compare differentially expressed proteomic in BLM induced IPF mice models and control models to evaluate protocols for optimal high-throughput data analysis.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD027900 | Pride
Lung Ipf Bleomycin 
UnknownTSSK4 upregulation in alveolar epithelial type-II cells facilitates pulmonary fibrosis through HSP90-AKT signaling restriction and AT-II apoptosis.
Not available
S-EPMC8514558 | biostudies-literature
UnknownMacrophages evoke autophagy of hepatic stellate cells to promote liver fibrosis in NAFLD mice via the PGE2/EP4 pathway.
Not available
S-EPMC11071853 | biostudies-literature
UnknownFerroptotic alveolar epithelial type II cells drive TH2 and TH17 mixed asthma triggered by birch pollen allergen Bet v 1.
Not available
S-EPMC10891108 | biostudies-literature
UnknownContribution of Pseudomonas aeruginosa - mediated club cell necroptosis to the bias of type 17 inflammation and steroid insensitivity in asthma.
Not available
S-EPMC12536588 | biostudies-literature
ProteomicsFKBP8 affinity mass spectrometry
Myc-FKBP8 affinity purification mass spectrometry was performed in FKBP8 knockout (KO) HEK293T and FKBP8 KO HeLa cells.
ORGANISM(S): Homo Sapiens 
2026-06-02 | PXD079162 |
ProteomicsRepurposing E3 ubiquitin ligases as cell surface protein degraders using Proteolysis Targeting Antibodies
The majority of current therapeutics targeting plasma membrane receptors function by antagonizing ligand binding or enzymatic activities. Typical mammalian proteins, however, consist of multiple domains executing discrete but coordinated activities, and saturating inhibition of one functional domain...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-25 | MSV000089542 | MassIVE
UnknownCombination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension. A Double-Blind Placebo-controlled Clinical Trial.
Not available
S-EPMC7068822 | biostudies-literature
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