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UnknownIdentification of Peptide Antagonists to Thioredoxin Glutathione Reductase of Schistosoma japonicum.
Schistosomiasis is one of the world's major public health problems. Praziquantel is currently the only effective drug against schistosomiasis. As resistance of praziquantel has emerged in some endemic areas, development of new antischistosomal agents should be a high priority. In this study, a phage...
S-EPMC6008883 | biostudies-literature
UnknownAlteration of brain metabolism in lacunar stroke based on 18F-FDG-PET/MRI analysis.

Background and purpose

Lacunar stroke (LS) is caused by occlusion of the penetrating branches of the major cerebral arteries and includes small and deep infarcts. Our study aimed to explore brain metabolic alterations in LS.

Methods

Seventy individuals with LS (aged 53.89 ± 1.198 year...
S-EPMC12834746 | biostudies-literature
TranscriptomicsNon-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy), 1 and 4 weeks after exposure. Gene expression that is modified under these parameters were compared between Tgfb1 wild type and heterozygote li...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-18216 | biostudies-arrayexpress
UnknownPemigatinib in previously treated Chinese patients with locally advanced or metastatic cholangiocarcinoma carrying FGFR2 fusions or rearrangements: A phase II study.

Objective

This study evaluated the antitumor activity and safety of pemigatinib in previously treated Chinese patients with advanced cholangiocarcinoma and fibroblast growth factor receptor 2 (FGFR2) fusions or rearrangements.

Background

Pemigatinib provided clinical benefits for prev...
S-EPMC9972033 | biostudies-literature
UnknownA 14-year multi-institutional collaborative study of Chinese pelvic floor surgical procedures related to pelvic organ prolapse.

Background

It has been a global trend that increasing complications related to pelvic floor surgeries have been reported over time. The current study aimed to outline the development of Chinese pelvic floor surgeries related to pelvic organ prolapse (POP) over the past 14 years and investiga...
S-EPMC7817324 | biostudies-literature
UnknownDiagnosis and treatment recommendations for glucose transporter 1 deficiency syndrome.

Background

Glucose transporter 1 deficiency syndrome (Glut1DS) was initially reported by De Vivo and colleagues in 1991. This disease arises from mutations in the SLC2A1 and presents with a broad clinical spectrum. It is a treatable neuro-metabolic condition, where prompt diagnosis and initi...
S-EPMC11885374 | biostudies-literature
ProteomicsFGL1 IP-MS data in 293T cell lysates
We immunoprecipitated exogenously expressed Myc-FGL1 using Anti-Myc-Tag monoclonal antibody (DIA-AN, Wuhan, China, Cat#2097) from 293T cells cocultured with tumor associated macrophages (TAMs) for 16 hr. No FGL1 protein was identified in protein lysates in which normal mouse IgG (Santa Cruz, Califor...
ORGANISM(S): Homo Sapiens 
2023-10-03 | PXD045948 |
ProteomicsUtilization of cross-linking mass spectrometry (XL-MS) for structural analysis of the ApoD-CD36 protein interaction
Structural analysis of the ApoD-CD36 complex by XL-MS.
ORGANISM(S): Homo Sapiens 
2025-11-20 | PXD070975 |
ProteomicsLiquid chromatography-mass spectrometry (LC-MS) for comparative proteomic analysis of human brain, lung, and kidney mural cells
We isolated PDGFRβ+ mural cells from tumor-adjacent normal human brain, lung, and kidney tissues. After lysis, we used LC-MS to profile differentially expressed proteins across these three cell types.
ORGANISM(S): Homo Sapiens 
2025-11-20 | PXD071101 |
ProteomicsLiquid chromatography-mass spectrometry (LC-MS) analysis of proteins co-immunoprecipitated with ApoD from endothelial-pericyte co-culture lysates
Liquid chromatography-mass spectrometry (LC-MS) analysis of the anti-ApoD immunoprecipitate.
ORGANISM(S): Homo Sapiens 
2025-11-20 | PXD071099 |
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