Sort   by:  
 Page size 
MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
MetabolomicsMicroRNA-mediated regulation of lipid metabolism in virus-infected Emiliania huxleyi.
The interactions between Emiliania huxleyi and E. huxleyi virus (EhV) regulate marine carbon and sulfur biogeochemical cycles and play a prominent role in global climate change. As a large DNA virus, EhV has developed a novel 'virocell metabolism' model to meet its high metabolic needs. Although it ...
2024-01-16 | MTBLS5178 | MetaboLights
MetabolomicsEffects of MeJA on Arabidopsis metabolome under endogenous JA deficiency
Jasmonates (JAs) play important roles in plant growth, development and defense. Comprehensive metabolomics profiling of plants under JA treatment provides insights into the interaction and regulation network of plant hormones. Here we applied high resolution mass spectrometry based metabolomics appr...
2017-10-23 | MTBLS375 | MetaboLights
UnknownThe genetic predisposition to bronchopulmonary dysplasia.
Not available
S-EPMC4853271 | biostudies-literature
UnknownGANT61 suppresses proliferation and induces apoptosis in ALK-Positive anaplastic large cell lymphoma via modulating the Hh-PIK3IP1-Akt signaling axis.
Not available
S-EPMC12827395 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownElectroacupuncture potentiates peripheral CB2 receptor-inhibited chronic pain in a mouse model of knee osteoarthritis.
Not available
S-EPMC6231462 | biostudies-literature
ProteomicsFunctional insights into protein acetylation in the hyperthermophilic archaeon Sulfolobus islandicus
Proteins undergo acetylation at the Nε-amino group of lysine residues and the Nα-amino group of the N-terminus in Archaea as in Bacteria and Eukarya. However, the extent, pattern and roles of the modifications in Archaea remain poorly understood. Here we report the proteomic analyses of a wild-type ...
ORGANISM(S): Sulfolobus islandicus REY15A 
2019-06-12 | PXD012246 | Pride
Quantitative proteomics Protein acetylome Gene deletion Mutant phenotype N-terminal acetyltransferase Protein lysine acetyltransferase 
ProteomicsProtein modification by a eukaryotic-like ubiquitin-related modifier in the hyperthermophilic archaeon Saccharolobus islandicus
Three independent analyses of Urm1 conjugation sites in the proteome of S. islandicus urm1 H81R strain were conducted. The data were analyzed using MaxQuant (v.1.6.15.0), and modified peptides were identified using a stringent standard.
ORGANISM(S): Sulfolobus islandicus REY15A 
2025-08-21 | PXD057602 | Pride
Saccharolobus islandicus Knockdown Urm1 Substrate 
UnknownDevelopment of a simple and miniaturized sandwich-like fluorescence polarization assay for rapid screening of SARS-CoV-2 main protease inhibitors.
Not available
S-EPMC8645223 | biostudies-literature
Sort   by:  
 Page size