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Shotgun (bottom-up) approach has been widely applied in large-scale proteomics studies. The inherent shortages of shotgun approach lie in that the generated peptides often overwhelm the analytical capacity of current LC-MS/MS systems and that abundant proteins often hamper the identification of prot...
ORGANISM(S): Homo sapiens (Human) 
2017-11-30 | PXD007863 | Pride
Plasma proteins are considered to be the most informative source of biomarkers for disease diagnosis and monitoring. Mass spectrometry (MS)-based proteomics has been applied to discover biomarkers in plasma, but the complexity of plasma proteins and the extremely large dynamic range of protein abund...
ORGANISM(S): Homo sapiens (Human) 
2024-05-23 | PXD048186 | Pride
Pancreatic cancer is a leading cause of cancer death worldwide. Cytoplasmic polyadenylation element binding protein 1 (CPEB1) is a fundamental translation regulatory factor regulating the polyadenylation process of messenger RNA. However, its biological functions in pancreatic cancer are poorly unde...
ORGANISM(S): Homo sapiens (Human) 
2024-07-03 | PXD047241 | Pride
SEPHS2, a key enzyme in synthesizing selenoproteins, which converts hydrogen selenide into selenophosphate. Here we provide the proteome of SEPHS2 knockout human A375 celllines.
ORGANISM(S): Homo Sapiens 
2026-03-25 | PXD076137 |
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