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MetabolomicsMetabolomic Profiling of the Striatum in Shank3 Knockout ASD Rats: Effects of Early Swimming Regulation

OBJECTIVE: This study aimed to investigate the regulatory impact of early swimming intervention on striatal metabolism in Shank3 gene knockout ASD model rats.

METHODS: Shank3 gene knockout exon 11-21 male 8-day-old SD rats were used as experimental subject...

2024-09-27 | MTBLS8577 | MetaboLights
ProteomicsThe proteomics analysis of Crassostrea gigas under Zn and Cd contamination
Understanding organisms’ environmental adaptation mechanisms is a fundamental question in ecology and evolution. The oyster Crassostrea gigas is able to accumulate high levels of zinc (Zn) and cadmium (Cd) without self-poisoning, and is thus widely used for pollution detection. However, the molecula...
ORGANISM(S): Crassostrea gigas (Pacific oyster) (Crassostrea angulata) 
2018-10-25 | PXD003290 | Pride
Proteomics Crassostrea Ecotoxicology Heavy-metal 
ProteomicsInterplay between acetylation and ubiquitination of Isw1 confers multidrug resistance in Cryptococcus neoformans
Lysine acetylation and ubiquitination are one of many protein modifications and play a crucial role in the biological regulation of many organisms, but little is known about the relationship between acetylation and ubiquitination few. Here, the Isw1 protein is an important member of the chromatin re...
ORGANISM(S): Candida albicans (Yeast) 
2022-12-26 | PXD037150 | Pride
Acetylation  ubiquitination  multidrug resistance 
ProteomicsInfluence of polysaccharides from Polygonatum kingianum on short-chain fatty acid production and quorum sensing in Lactobacillus faecis
Set the bacteria solution without polysaccharides from Polygonatum kingianum(PS) as the control group (CON group), and the bacteria solution with PS added as the administration group (PS group), the target strain treated with and without PS (20 μg/mL) was used for proteomic analysis.
ORGANISM(S): Lactobacillus sp. Y10 
2022-02-16 | PXD029210 | Pride
Lactobacillus faecis 
UnknownCharacterization of a novel two-component Na+(Li+, K+)/H+ antiporter from Halomonas zhaodongensis.
Not available
S-EPMC5484666 | biostudies-literature
ProteomicsPodophyllum Hexandrum Royle MALDI-TOF-MS/MS
With the aim of reveal the mechanism of Podophyllum Hexandrum Royle adaption to high altitude, MALDI-TOF-MS/MS in combination with 2-DE was used to identify the differentially expressed proteins in leaves of Podophyllum Hexandrum Royle between low altitude (2200m) and high altitude (3100m), 65 diffe...
ORGANISM(S): Sinopodophyllum hexandrum 
2023-03-10 | PXD005640 | Pride
Podophyllum hexandrum royle Altitude Maldi-tof-ms/ms 
MetabolomicsFlavonoid Biosynthesis Is Likely More Susceptible to Elevation and Tree Age Than Other Branch Pathways Involved in Phenylpropanoid Biosynthesis in Ginkgo Leaves
Ginkgo leaves are always resources for flavonoids pharmaceutical industry. However, the effect of the elevation and tree age changes on flavonoid biosynthesis have not been detailly explored in Ginkgo leaves. In addition, whether these environmental pressures have similar effects on the biosynthesis...
2020-12-14 | MTBLS962 | MetaboLights
MetabolomicsDynamic metabolic and transcriptomic profiling reveals the biosynthetic characteristics of hydroxycinnamic acid amides (HCAAs) in sunflower pollen

Sunflower pollen is a natural nutritious food with a long history and multiple functions, however, the main chemical components apart from flavonoids and their biosynthesis processes have not been thoroughly investigated. In this study, seven hydroxycinnamic acid amides (HCAAs) (1-7) abundant in ...

2021-10-15 | MTBLS3075 | MetaboLights
UnknownLithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling.
Not available
S-EPMC5482734 | biostudies-literature
TranscriptomicsGene expression profiles of hepatocyte-like cells derived from induced pluripotent stem cells (iPSCs) from donors with the Zellweger spectrum of peroxisome biogenesis disorders (PBD-ZSD) and healthy controls
Skin fibroblasts from individuals with PBD-ZSD, a rare autosomal recessive disorder caused by peroxisome assembly defects, show defects in lipid metabolism that provide the basis for clinical diagnostic tests, but are not among the cell types most affected by disease. To explore phenotypes of more c...
ORGANISM(S): Homo sapiens 
2015-05-21 | E-GEOD-69066 | biostudies-arrayexpress
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