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Inherited retinal diseases (IRDs) encompass a genetically diverse group of conditions in which mutations in genes critical to retinal function lead to progressive loss of photoreceptor cells and subsequent visual impairment. A handful of ribosome-associated genes have been implicated in retinal diso...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD045660 | Pride
The dataset includes the sequencing data of m6A-high and m6A-low LUAD tissues, each of which contains five biological replicates. A total of 3437 protein groups were obtained, 407 differential proteins were obtained . Exerllent repeatability for different biological replicates is indicated based on...
ORGANISM(S): Homo Sapiens 
2021-07-29 | PXD027633 |
Phase separated p62 body plays pivotal roles during autophagosome formation, however, the underlying mechanisms are still not fully understood. Mass spectrometry-based proteomics revealed significant enrichment of vesicle trafficking components within p62 bodies.
ORGANISM(S): Homo Sapiens Rattus Norvegicus 
2023-06-09 | PXD038262 |
Molecular mechanisms of HIV-1 latency have been studied extensively to achieve a functional cure for the acquired immunodeficiency syndrome (AIDS). To develop more promising latency-reversing agents (LRAs) to efficiently reactivate the latent reservoir which is subsequently eliminated by immune surv...
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD031011 |
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