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TranscriptomicsGuselkumab (interleukin-23-specific monoclonal antibody) demonstrates clinical and molecular response in moderate-to-severe psoriasis
A gene expression profiling study was conducted in which skin biopsy samples were collected for RNA extraction and hybridization to microarrays from patients with moderate-to-severe psoriasis who participated in the phase 1, guselkumab first-in-human randomized, double-blind, placebo-controlled tria...
ORGANISM(S): Homo sapiens 
2014-05-14 | E-GEOD-51440 | biostudies-arrayexpress
UnknownExpression of oncogenic HRAS in human Rh28 and RMS-YM rhabdomyosarcoma cells leads to oncogene-induced senescence.
Not available
S-EPMC8363632 | biostudies-literature
GenomicsA Case-Controlled Study for Genotype-Phenotype Associations in Multiple Sclerosis (MS)

This is a multi-centre, case-controlled study to develop a dataset containing 1000 MS cases and 1000 matched controls and to associate DNA sequence (allelic) variations with MS phenotypes.

Study subjects were enrolled through a prospective effort initiated in 2003. Three MS clinical ce...

phs000171.v1.p1 | EGA
Transcriptomicslongitudinal expression profiling in whole blood of multiple sclerosis patients and controls [MS vs Ctrl Discovery dataset]
Multiple sclerosis is the most common autoimmune disease of the central nervous system. Studying whole blood RNA from a cohort of 195 MS patients and 66 healthy controls, we identified gene expression signatures for interferon treatment and disease status by microarray analysis. Blood was collected ...
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41848 | biostudies-arrayexpress
Transcriptomicslongitudinal expression profiling in whole blood of multiple sclerosis patients and controls [IFN_discovery dataset]
Multiple sclerosis is the most common autoimmune disease of the central nervous system. Studying whole blood RNA from a cohort of 195 MS patients and 66 healthy controls, we identified gene expression signatures for interferon treatment and disease status by microarray analysis. Blood was collected ...
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41846 | biostudies-arrayexpress
Transcriptomicslongitudinal expression profiling in whole blood of multiple sclerosis patients and controls [IFN_replication dataset]
Multiple sclerosis is the most common autoimmune disease of the central nervous system. Studying whole blood RNA from a cohort of 195 MS patients and 66 healthy controls, we identified gene expression signatures for interferon treatment and disease status by microarray analysis. Blood was collected ...
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41847 | biostudies-arrayexpress
TranscriptomicsLongitudinal expression profiling in whole blood of multiple sclerosis patients and controls
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41850 | biostudies-arrayexpress
ProteomicsGlycoproteoforms of osteoarthritis-associated lubricin in plasma and synovial fluid
Lubricin or proteoglycan-4 (PRG-4) is a mucinous glycoprotein that lubricates the cartilage and maintains normal tissue function and cell homeostasis. Altered O- glycoproteforms of lubricin have been found in osteoarthritis (OA) synovial fluid (SF), which could ostensibly be used as a biomarker to...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055049 | Pride
Human Oa Lc-ms Synovial fluid Plasma Lubricin 
UnknownOlink Proteomic Profiling of Vitreous Humor and Plasma From Proliferative Diabetic Retinopathy Patients Identifies a Novel Inflammatory Molecular Endotype.
Not available
S-EPMC12831140 | biostudies-literature
UnknownBiological and structural characterization of a host-adapting amino acid in influenza virus.
Not available
S-EPMC2916879 | biostudies-literature
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