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Genes containing multiple polyadenylation (polyA) sites express mRNA isoforms with variable 3’ untranslated regions (3’UTRs). We found that short and long 3’UTR isoforms were relatively more abundant when genes were highly and lowly expressed, respectively, in human and mouse cells. Consistently, up...
ORGANISM(S): Mus musculus 
IDO1 interacting proteins in two colorectal cancer cells and was subjected to beads, and the beads were washed by buffer and identified by mass spectrometry (MS)
ORGANISM(S): Homo Sapiens 
2022-05-05 | PXD033718 |
Alternative cleavage and polyadenylation (APA) results in mRNA isoforms containing different 3’ untranslated regions (3’UTRs) and/or coding sequences. How core cleavage and polyadenylation (C/P) factors regulate APA is not well understood. Using siRNA knockdown coupled with deep sequencing, we found...
ORGANISM(S): Mus musculus 
Alternative cleavage and polyadenylation (APA) generates diverse mRNA isoforms. We developed 3' region extraction and deep sequencing (3'READS) to address mispriming issues that commonly plague poly(A) site (pA) identification, and we used the method to comprehensively map pAs in the mouse genome. T...
ORGANISM(S): Mus musculus 
provide new perspectives and important resources for further exploring bioluminescence origin and evolution in insects
ORGANISM(S): Luciola Terminalis 
provide new perspectives and important resources for further exploring bioluminescence origin and evolution in insects
ORGANISM(S): Lamprigera Yunnana 
PFOS and PFOA are persistent organic pollutants known to impair human reproduction, but their effects and molecular mechanisms on human sperm remain unclear. Here, we conducted comprehensive proteomic and phosphoproteomic profiling of human sperm exposed to PFOS and PFOA during capacitation to provi...
ORGANISM(S): Homo Sapiens 
4D label-free quantitative proteomics was performed to analysis the changes of protein expression in synovial tissues between Normal control group, Model control group and JTQBG treated group.
ORGANISM(S): Rattus Norvegicus 
2024-02-23 | PXD050056 |
islation of AD mitochondrial and then detect the changes
ORGANISM(S): Mus Musculus 
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