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UnknownStress Hyperglycemia Ratio and Adverse Outcomes in Acute Mild Ischemic Stroke or High-Risk Transient Ischemic Attack: A Secondary Analysis of the INSPIRES Trial.
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S-EPMC12829502 | biostudies-literature
TranscriptomicsTranscriptional activity regulates alternative cleavage and polyadenylation
Genes containing multiple polyadenylation (polyA) sites express mRNA isoforms with variable 3’ untranslated regions (3’UTRs). We found that short and long 3’UTR isoforms were relatively more abundant when genes were highly and lowly expressed, respectively, in human and mouse cells. Consistently, up...
ORGANISM(S): Mus musculus 
2011-08-15 | E-GEOD-26512 | biostudies-arrayexpress
ProteomicsUSP14 Promotes Tryptophan Metabolism and Immune Suppression by Stabilizing IDO1 in Colorectal Cancer
IDO1 interacting proteins in two colorectal cancer cells and was subjected to beads, and the beads were washed by buffer and identified by mass spectrometry (MS)
ORGANISM(S): Homo Sapiens 
2022-05-05 | PXD033718 |
TranscriptomicsRegulation of alternative cleavage and polyadenylation by 3’ end processing and splicing factors
Alternative cleavage and polyadenylation (APA) results in mRNA isoforms containing different 3’ untranslated regions (3’UTRs) and/or coding sequences. How core cleavage and polyadenylation (C/P) factors regulate APA is not well understood. Using siRNA knockdown coupled with deep sequencing, we found...
ORGANISM(S): Mus musculus 
2015-04-01 | E-GEOD-62001 | biostudies-arrayexpress
TranscriptomicsAnalysis of alternative cleavage and polyadenylation by 3' region extraction and deep sequencing
Alternative cleavage and polyadenylation (APA) generates diverse mRNA isoforms. We developed 3' region extraction and deep sequencing (3'READS) to address mispriming issues that commonly plague poly(A) site (pA) identification, and we used the method to comprehensively map pAs in the mouse genome. T...
ORGANISM(S): Mus musculus 
2012-12-17 | E-GEOD-42398 | biostudies-arrayexpress
Proteomics4D label-free quantitative proteomics analysis of collagen-induced arthritis rats
4D label-free quantitative proteomics was performed to analysis the changes of protein expression in synovial tissues between Normal control group, Model control group and JTQBG treated group.
ORGANISM(S): Rattus Norvegicus 
2024-02-23 | PXD050056 |
ProteomicsDetermination of high flavor-active peptides in tilapia hydrolysate using LC-MS/MS
Determination of highly flavor-active peptides in tilapia hydrolysates using LC-MS/MS with the aim of identifying potentially salty peptides in tilapia byproduct hydrolysates
ORGANISM(S): Oreochromis Niloticus 
2023-12-06 | PXD047590 |
Proteomics5xFAD mitochondrial Data-independent acquisition
islation of AD mitochondrial and then detect the changes
ORGANISM(S): Mus Musculus 
2022-04-03 | PXD032992 |
ProteomicsA Comprehensive Proteomics Analysis Reveals Dynamic Phenotypes of Tumor-associated Macrophages and Their Precursor Cells in Tumor Progression
Tumor-associated macrophages (TAMs) are key regulators in tumor progression. Although a role of bone marrow-derived monocytes (Mons) as TAM precursors has been revealed, the dynamic phenotypes of both TAMs and Mons regulated by the tumor microenvironment remain unclear. Here, we constructed an optim...
ORGANISM(S): Mus Musculus 
2023-10-30 | PXD046492 |
ProteomicsLRRC71 is essential for sperm motility, fertilization and male fertility
Although sperm supply half the genomic material necessary for generating viable offspring in sexual reproduction, the core molecular mechanisms underlying their formation remain largely unelucidated. Here, we demonstrate that leucine-rich repeat-containing 71 (LRRC71) is essential for spermatogenesi...
ORGANISM(S): Mus Musculus 
2026-04-29 | PXD077837 |
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