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UnknownSystems pharmacology approaches decipher the anti-cancer efficacy of ethnopharmacological agents in hepatocellular carcinoma.
Not available
S-EPMC12711885 | biostudies-literature
UnknownA Novel <i>Rhodotorula evergladensis</i> CXCN-6 Rich in Torularhodin and PUFAs with Potent Antioxidant and Anti-Inflammatory Activities.
Not available
S-EPMC12729354 | biostudies-literature
ProteomicsLoss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella
Aberrant sperm flagella impair sperm motility and cause male infertility, yet the genes which have been identified in multiple morphological abnormalities of the flagella (MMAF) can only explain the pathogenic mechanisms of MMAF in a small number of cases. Here, we identify and functionally characte...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD011730 | Pride
Mutation Sperm flagella Morphological abnormalities Proteomics analysis 
ProteomicsLabel-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line
Hepatitis B virus (HBV) infection is a major health problem worldwide. Recent evidence suggests that various viruses can manipulate the infection process by secretion of specific viral and cellular components into exosomes, small nanometer-sized (30-150 nm) vesicles secreted from various cells. Howe...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080718 | MassIVE
ProteomicsGlobal Phosphoproteomic Analysis Reveals Significant Metabolic Reprogramming in the Termination of Liver Regeneration in Mice
Phosphorylation is well-known in regulating various biological processes. However, comprehensively phosphoproteomic profiling in the termination of liver regeneration (LR) is still missing. Here, we used TMT labeling coupled with phosphopeptides enrichment and 2D LC-MS/MS analysis to establish a glo...
ORGANISM(S): Mus musculus (Mouse) 
2020-03-04 | PXD011374 | Pride
Phosphorylation  partial hepatectomy  liver regeneration  metabolic reprogramming 
ProteomicsAlterations of human plasma proteome profile on adaptation to high-altitude hypobaric hypoxia
For individuals migrating to or residing permanently at high-altitude regions, environmental hypobaric hypoxia is a primary challenge which induces several physiological or pathological responses. It is well documented that human beings adapt to hypobaric hypoxia via some protective mechanisms, such...
ORGANISM(S): Homo sapiens (Human) 
2019-03-27 | PXD012221 | Pride
Proteomics  high altitude  hypobaric hypoxia  complement and coagulation cascades  antioxidant  glycolysis. 
ProteomicsMyocardial Injury Caused by Chronic Alcohol Exposure——A Pilot Study Based on Proteomic
Chronic alcohol exposure can cause myocardial degenerative diseases, manifested as cardiac insufficiency, arrhythmia, etc. These are defined as alcoholic cardiomyopathy (ACM). Alcohol-mediated myocardial injury has previously been studied through metabolomics, and it has been proved to be involved i...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD032949 | Pride
Alcoholic cardiomyopathy  proteomics  differentially expressed proteins  kegg pathway  myocardial injury 
ProteomicsProteomic analysis of lysine acetylation provides strong evidence for involvement of acetylated histone and chloroplast proteins in CWMV infected plant
Protein lysine acetylation (Kac) is an important post-translational modification (PTM) mechanism in both eukaryotes and prokaryotes, with key roles in cellular regulation. To investigate the role of Kac in plants infected with virus, we characterized the lysine acetylome of Nicotiana benthamiana pla...
ORGANISM(S): Nicotiana tabacum (Common tobacco) 
2021-05-07 | PXD012537 | Pride
Lysine acetylation Cwmv Photosynthesis Histone h3 Chloroplast 
ProteomicsPBP inactivation and OXA treatment resulted in altered protein compositions of Staphylococcal membrane vesicles
The engineered Staphylococcus aureus strain RN4220Δagr/EDⅢ was treated with 1/4 MIC of Oxacillin (OXA), or used to construct pbp3 and pbp4 gene mutant strain. Then, the membrane vesicles (MVs) of parent strain (ΔagrMVs), OXA-treated strain (Δagr/OXAMVs), and pbp3/pbp4 mutants (Δagr/OXAMVs) were harv...
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Rn4220 
PXD057038 |
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