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Pediatric acute lymphoblastic leukemia (ALL) contains cytogenetically distinct subtypes that respond differently to cytotoxic drugs. Subtype classification can be also achieved through gene expression profiling. However, how to apply such classifiers to a single patient and correctly diagnose the di...
ORGANISM(S): Homo sapiens 
Revealing the reproductive mechanism of schistosomes will help to control this disease. In this study, the proteomic profiles of single-sex infected female (SF) worms and bisexual infected mature female (MF) worms of Schistosoma japonicum at 18, 21, 23 and 25 days post infection (dpi) were identifie...
ORGANISM(S): Schistosoma japonicum (Blood fluke) 
2024-01-26 | PXD030834 | Pride
The proteomics and phosphorylation proteomics of PP2Acα regulates cerebellar development via phosphorylation-dependent neuronal programs.
ORGANISM(S): Mus Musculus 
2025-11-28 | PXD071414 |
Protein misfolding is a contributor to the development of type 2 diabetes (T2D), but it is unknown whether impaired proteostasis in T2D is generalized or has special features. Here, we report a robust accumulation of misfolded proteins within the mitochondria of human pancreatic islets from patients...
ORGANISM(S): Homo sapiens (Human) 
2025-06-05 | PXD060404 | Pride
To identify the target protein of gp78 that regulates KAP1 phosphorylation, we conducted an analysis using liquid chromatography–tandem mass spectrometry (LC–MS/MS), which identified several putative target proteins.
ORGANISM(S): Homo Sapiens 
Here, we report a simple, rapid, and practical approach of mass-adaptive coating-assisted single-cell proteomics (Mad-CASP). Combined with the designed synthetic peptides and novel data acquisition strategy, 1240 ± 93 (n = 3) proteins were identified from a single HeLa cell by Mad-CASP.
ORGANISM(S): Homo Sapiens 
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