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UnknownIdentification of miRNA biomarkers for essential hypertension in small samples based on MPGAM.
Not available
S-EPMC12559234 | biostudies-literature
ProteomicsThe crosstalk between CRL5 and APC/C E3 ligases regulates metastasis and chemo-sensitivity of cancer cells
Cullin-RING ligases (CRLs) and the anaphase-promoting complex/cyclosome (APC/C) are two major multi-subunit ubiquitin ligases essential for protein homeostasis. The underlying mechanism and biological consequence of their crosstalk remain elusive. Here, we employed tandem affinity purification follo...
ORGANISM(S): Homo sapiens (Human) 
2026-01-23 | PXD068961 | Pride
Cul5  apc11  neddylation  metastasis  chemo-sensitivity 
UnknownBRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1-mediated deubiquitination of CHK1.
Not available
S-EPMC10457387 | biostudies-literature
UnknownRHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis.
Not available
S-EPMC11832924 | biostudies-literature
UnknownRibosomal protein S27-like regulates autophagy via the β-TrCP-DEPTOR-mTORC1 axis.
Not available
S-EPMC6234217 | biostudies-literature
UnknownDEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals.
Not available
S-EPMC7018663 | biostudies-literature
ProteomicsA Tissue-Specific Atlas of Mouse N-Glycoproteome
In this study, we employed StrucGP to generate the first high-resolution and site-specific N- glycoproteomic atlas across 24 diverse mouse tissues. This comprehensive dataset provides an unprecedented insight into the tissue-specific landscape of N-glycosylation, revealing how distinct glycan struct...
ORGANISM(S): Mus Musculus 
2025-05-07 | PXD063701 |
TranscriptomicsTranscriptome signature in early biopsies of stably functioning kidney allografts identify patients at risk for chronic injury
Chronic injury in kidney transplants remains a major cause of graft loss. The aim of this study was to identify a predictive gene set capable of classifying renal grafts at risk for progressive injury due to fibrosis.The Genomics of Chronic Allograft Rejection (GoCAR) study is a prospective, multice...
ORGANISM(S): Homo sapiens 
2016-07-20 | E-GEOD-57387 | biostudies-arrayexpress
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