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ProteomicsIn-vitro culture of single gut bacterial strains with added sugars
Gut commensal bacterial strains were cultured with or without added sugars (glucose, sucrose and kestose). The base culture medium without sugar added were modified based on the Yeast Casitone Fatty Acids (YCFA) broth. Samples were analyzed for proteomics using LC-MS/MS.
ORGANISM(S): Blautia hydrogenotrophica DSM 10507 Bacteroides thetaiotaomicron Escherichia coli Phocaeicola vulgatus ATCC 8482 Bacteroides uniformis ATCC 8492 Bacteroides ovatus ATCC 8483 
2023-06-08 | PXD037923 | Pride
Proteomics Single strains Culturing 
GenomicsDynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells
We investigated genome-wide nucleosome coverage and histone methylation occupancies in somatic MEFs, intermediate pre-iPSCs and fully reprogrammed iPSCs. We found that nucleosome occupancies increased in promoter regions and decreased in intergenic regions in pre-iPSCs and then recover to an interme...
ORGANISM(S): Mus musculus 
2015-12-13 | E-GEOD-60627 | biostudies-arrayexpress
ProteomicsIdentified potential interacting proteins of WRN
We used anti-WRN antibody to perform immunoprecipitation assay through oncosphere lysates and identified a potential interacting protein candidate
ORGANISM(S): Homo Sapiens 
PXD044847 |
ProteomicsIdentification of ANXA1 as A Novel Upstream Negative Regulator of Notch1 Function in AML
Abnormal Notch1 expression has an important role in tumorigenesis. However, upstream control mechanisms for Notch1 are still insufficiently understood. Acute myeloid leukemia (AML) is one of the most common and lethal blood malignancies with limited possibilities for treatment. Thus, new therapeutic...
ORGANISM(S): Homo Sapiens 
PXD056593 |
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