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MetabolomicsSacha inchi oil alleviates gut microbiota dysbiosis and improves hepatic lipid dysmetabolism in high-fat diet-fed rats
Dietary ω-3 polyunsaturated fatty acids (PUFAs) are beneficial for humans against the development of hyperlipidaemia, but the underlying mechanisms are still poorly understood. Here, we demonstrated that oral consumption of sacha inchi oil, which is rich in α-linolenic acid, alleviated dyslipidemia,...
2022-02-21 | MTBLS1225 | MetaboLights
ProteomicsThe protein interaction of PALM2 in HEK 293T
We identify the protein interaction of PALM2 in HEK 293T. we find that PALM2 can promote the malignant behaviors of esophageal squamous cancer cell (ESCC). Focusing on the mechanism inside, we reveal that PALM2 promotes the migration of esophageal squamous cancer cells through activating it interact...
ORGANISM(S): Homo Sapiens 
2023-03-08 | PXD040700 |
ProteomicsPrenylated PALM2 Promotes the Migration of Esophageal Squamous Cancer Cells through Activating Ezrin
Proteins containing a CAAX motif at the C-terminus can occur prenylation modification and regulate the localization and activity of a series of key regulatory proteins, including RAS superfamily members, heterotrimeric G proteins, nuclear lamina protein, and several protein kinases and phosphatases....
ORGANISM(S): Homo Sapiens 
2023-03-20 | PXD040969 |
GenomicsGonadal DNA methylomes of half-smooth tongue sole Cynoglossus semilaevis
Environmental sex determination (ESD) occurs in divergent, phylogenetically unrelated taxa, and in some species co-occurs with genetic sex determination (GSD) mechanisms. Although epigenetic regulation in response to environmental effects has long been proposed to be associated with ESD, a systemic ...
ORGANISM(S): Cynoglossus semilaevis 
2014-01-23 | E-GEOD-41129 | biostudies-arrayexpress
ProteomicsQuantitative proteomics of candidate biomarkers in NSCLC-derived extracellular vesicles using parallel reaction monitoring assay
Quantitative proteomics of candidate biomarkers in NSCLC-derived extracellular vesicles using parallel reaction monitoring assay
ORGANISM(S): Homo Sapiens 
2024-08-07 | PXD054691 |
TranscriptomicsEndothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells
Coronary arteriogenesis is a central step in cardiogenesis, requiring coordinated generation and integration of endothelial (EC) and vascular smooth muscle cells (SM). At present, it is unclear whether the cell fate program of cardiac progenitors to generate complex muscular or vascular structures i...
ORGANISM(S): Homo sapiens 
2015-12-15 | E-GEOD-75985 | biostudies-arrayexpress
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