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TranscriptomicsAMD3100 and G-CSF Mobilize Different CD34+ Cell Populations Based on Gene and miRNA Expression
Plerixafor (AMD3100) and G-CSF mobilize peripheral blood stem cells (PBSCs) by different mechanisms. A rhesus macaque model was used to compare plerixafor and G-CSF-mobilized CD34+ cells. Three PBSC concentrates were collected from 3 macaques treated with G-CSF, plerixafor, or plerixafor plus G-CSF....
ORGANISM(S): Macaca mulatta 
2009-12-04 | E-GEOD-16936 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Arabidopsis thaliana G protein subunit mutants in response to abscisic acid (ABA)
Heterotrimeric G proteins mediate crucial and diverse signaling pathways in eukaryotes. To gain insights into the regulatory modes of the G protein and the co-regulatory modes of the G protein and the stress hormone abscisic acid (ABA), we generated and analyzed gene expression in G protein subunit ...
ORGANISM(S): Arabidopsis thaliana 
2010-12-06 | E-GEOD-19520 | biostudies-arrayexpress
GenomicsNative G-quadruplexes Stabilization Impairs Transcription Initiation
Native G-quadruplexes Stabilization Impairs Transcription Initiation
PRJNA739982 | ENA
TranscriptomicsPro-tumorigenic effects of HLA-G in Renal Cell Carcinoma
Renal cell carcinoma (RCC) frequently exhibits high expression of the immunomodulatory molecule HLA-G, which promotes immune tolerance and tumor progression. To define the cell-intrinsic transcriptional programs driven specifically by HLA-G1 neo-expression, we generated RCC7/HLA-G1 cells by lentivir...
ORGANISM(S): Homo sapiens 
2026-05-01 | E-MTAB-16395 | biostudies-arrayexpress
TranscriptomicsTumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism
Global gene expression studies were performed to determine whether the granulocytic-like MDSC populations from G-CSF treated mice resembled those of tumor-bearing (TB) mice more so than those of the non-tumor-bearing control (i.e., WT) at a molecular level. Splenic CD11b+Gr-1high cell populations fr...
ORGANISM(S): Mus musculus 
2011-12-07 | E-GEOD-32209 | biostudies-arrayexpress
ProteomicsProteomic Analysis of Moorella thermoacetica-g-C3N4 Biohybrid system for Artificial Photosynthesis
Proteomic analysis was utilized to explore the effects on the microorganism induced by the carbon-based semiconductor. We then characterized the proteomic and changes of the proposed M. thermoacetica-g-C3N4 and Moorella thermoacetica-CdS hybrid system during light harvesting, and proposed the elect...
ORGANISM(S): Moorella Thermoacetica 
2024-06-16 | PXD053157 |
ProteomicsCo-immunoprecipitation of G-quadruplex-containing Core Promoter and nanoLC-FAMIS-MS/MS
G-quadruplexes (G4s) are noncanonical DNA secondary structures formed through the self-association of guanines, and they are distributed widely across the genome. G4 participates in multiple biological processes including gene transcription, and G4-targeted ligands serve as potential therapeutic age...
ORGANISM(S): Homo sapiens (Human) 
2021-07-19 | PXD026830 | Pride
Human Core promoter Co-immunoprecipitation G-quadruplex Nuclear protein Nanolc-famis-ms/ms 
TranscriptomicsProtein P Vs Protein G
Rationale: Respiratory syncytial virus (RSV) and Streptococcus pneumoniae are major respiratory pathogens. Co-infection with RSV and S. pneumoniae is associated with severe and often fatal pneumonia but the molecular basis for this remains unclear. Objectives: To determine if interaction between RS...
ORGANISM(S): Streptococcus pneumoniae D39 
2014-06-21 | E-GEOD-58424 | biostudies-arrayexpress
TranscriptomicsInfluence of oxygen limitation, absence of the cytochrome bc1 complex and low pH on global gene expression in Gluconobacter oxydans 621H using DNA microarray technology
The genome-wide transcriptional responses of the strictly aerobic -proteobacterium Gluconobacter oxydans 621H to oxygen limitation, to the absence of the cytochrome bc1 complex, and to low pH were studied using DNA microarray analyses. Oxygen limitation caused expression changes of 486 genes, repres...
ORGANISM(S): Gluconobacter oxydans 621H 
2012-03-23 | E-GEOD-34294 | biostudies-arrayexpress
TranscriptomicsGenistein Protects Hematopoietic Stem Cells against G-CSF-Induced DNA Damage
Granulocyte colony-stimulating factor (G-CSF) has been utilized to treat neutropenia in various clinical settings. Although clearly beneficial, there are concerns that use of G-CSF in certain conditions increases the risk of myelodysplastic syndrome (MDS) and/or acute myeloid leukemia (AML). The mos...
ORGANISM(S): Mus musculus 
2014-02-07 | E-GEOD-54737 | biostudies-arrayexpress
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