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TranscriptomicsTranscription profiling of mouse with Somatic loss of BRCA1 and p53 reveals their lossinduces mammary tumors with features of human BRCA1-mutated basal-like breast cancer
Not available
ORGANISM(S): Mus musculus 
2009-10-30 | E-NCMF-6 | biostudies-arrayexpress
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
Genomicsena-DATASET-BGI-26-11-2015-07:58:13:440-13 - samples
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAD00001001691 | EGA
GenomicsWhole-genome sequencing in 14 cases and whole-exome sequencing in 90 cases of Chinese ESCC
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAS00001001487 | EGA
TranscriptomicsGene expression profiles of nasopharyngeal carcinoma cell line HNE2 following TP53 overexpression
Recent studies have revealed that long non-coding RNAs (lncRNAs) participate in all steps of cancer initiation and progression by regulating protein coding genes at the epigenetic, transcriptional and post-transcriptional levels. LncRNAs are in turn regulated by other genes, forming a complex regula...
ORGANISM(S): Homo sapiens 
2015-05-14 | E-GEOD-60379 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of mouse Brca1 and Brca2 mammary tumors
Comparison of mammary tumors from 35 Brca1F/F;p53F/F, 62 Brca2F/F;p53F/F and 33 p53F/F mice. For each mouse, tumor DNA was hybridized with its spleen DNA as a reference.
ORGANISM(S): Mus musculus 
2010-12-15 | E-NCMF-34 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of mouse Brca1 and Brca2 mammary tumors
Comparison of mammary tumors from 35 Brca1F/F;p53F/F, 62 Brca2F/F;p53F/F and 33 p53F/F mice. For each mouse, tumor DNA was hybridized with its spleen DNA as a reference.
ORGANISM(S): Mus musculus 
2010-12-15 | E-NCMF-35 | biostudies-arrayexpress
ProteomicsDivalent Aptamer-mediated Clustering for Extracellular Vesicle Separation
Extracellular vesicles (EVs) are important mediators of intercellular communication and promising sources of diagnostic and therapeutic biomarkers, yet effective EV isolation remains challenging due to trade-offs among yield, purity, and adaptability across biofluids. Here, we introduce divalent apt...
ORGANISM(S): Homo Sapiens 
2026-05-03 | PXD078053 |
TranscriptomicsTranscription profiling of Brca1- and p53-deficient mouse mammary tumors to treatment with doxorubicin, docetaxel or cisplatin
We have studied in vivo responses of spontaneous Brca1- and p53-deficient mouse mammary tumors to treatment with doxorubicin, docetaxel or cisplatin.
ORGANISM(S): Mus musculus 
2007-06-18 | E-NCMF-5 | biostudies-arrayexpress
TranscriptomicsPromoter hypermethylation of TERT is associated with hepatocellular carcinoma in the Han Chinese population
A recent study by Castelo-Branco, P., et al. Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study. Lancet Oncol 2013;14:534-542 found upstream of the transcription start site (UTSS) hypermethylation of TERT is associated with...
ORGANISM(S): Homo sapiens 
2015-01-03 | E-GEOD-63863 | biostudies-arrayexpress
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