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Newcastle disease (ND) is an acute, febrile, and highly contagious disease caused by the virulent Newcastle disease virus (vNDV) worldwide. The disease causes serious economic losses to the poultry industry. However, the metabolic changes caused by vNDV infection remain unclear. The objective of thi...
2019-12-20 | MTBLS1115 | MetaboLights
3-Hydroxy-3-methylglutaryl-CoA synthase (HMGS) is the second enzyme in the mevalonate pathway. F-244 is the specific inhibitor of HMGS. F-244 treatment caused reduced primary root growth. SWATH-MS quantitative proteomics analysis was carried out to identify differential expressed proteins in F-244-t...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-10-01 | PXD009776 | Pride
3-Hydroxy-3-methylglutaryl-CoA synthase (HMGS) is the second enzyme in the mevalonate pathway. While the recombinant Brassica juncea HMGS1 (BjHMGS1) mutant S359A displayed 10-fold higher enzyme activity than wild-type (wt) BjHMGS1, transgenic tobacco overexpressing S359A (OE-S359A) exhibited greater...
ORGANISM(S): Nicotiana tabacum (Common tobacco) 
2021-01-04 | PXD006869 | Pride
A549 cells were infected with NDV at a multiplicity of infection (MOI) of 3 at 37°C, and the cells were collected 24 hours post-infection.
ORGANISM(S): Homo Sapiens 
2025-11-07 | PXD070444 |
Regulatory T (Treg) cells characterized by expression of the transcription factor forkhead box P3 (Foxp3) maintain immune homeostasis by suppressing self-destructive immune responses1-4. Foxp3 operates as a late acting differentiation factor controlling Treg cell homeostasis and function5, whereas ...
ORGANISM(S): Mus musculus 
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