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ProteomicsStructural basis of MICAL autoinhibition
MICAL proteins play a crucial role in cellular dynamics by binding and disassembling actin filaments, impacting processes like axon guidance, cytokinesis, and cell morphology. Their cellular activity is tightly controlled, as dysregulation can lead to detrimental effects on cellular morphology. Alth...
ORGANISM(S): Homo sapiens (Human) 
2024-10-30 | PXD057312 | Pride
F-actin depolymerization Actin Autoinhibition Rab Mical 
MetabolomicsTranscript, protein and metabolite temporal dynamics in the CAM plant Agave
Already a proven mechanism for drought sustainability, crassulacean acid metabolism (CAM) is a specialized type of photosynthesis that maximizes water-use efficiency (WUE) via an inverse (compared to C3 and C4 photosynthesis-performing species) day/night pattern of stomatal closure/opening to shift ...
2017-10-13 | MTBLS363 | MetaboLights
UnknownAging Aggravates Cachexia in Tumor-Bearing Mice.
Not available
S-EPMC8750471 | biostudies-literature
UnknownInfection of male rats with Toxoplasma gondii results in enhanced delay aversion and neural changes in the nucleus accumbens core.
Not available
S-EPMC4455797 | biostudies-literature
OtherProteomics of muscle chronological ageing in post-menopausal women.
Data from ProteomeXchange, PXD ID: PXD001527. File: E-PP-proteolyse-682(1179).mgf Published as part of BMC Genomics. 2014 15:1165 . From the Abstract: {{i}} Muscle samples were compared between adult (56 years) and old (78 years) post-menopausal women. In addition to total muscle extracts, low-ioni...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32310006844 | GPMDB
Resource Reanalysis 
TranscriptomicsDynamics of Virus-specific CD8+ T cells in the Human Nasal Cavity
The goal of this experiment is to compare the transcriptomic profile of CD8+ T cells isolated from the nasal cavity and whole blood at two different state, baseline and CD3/28 activated. This will allow us to characterise the unique features of CD8+ T cells in the nasal cavity. We isolated CD8+CD4...
ORGANISM(S): Homo sapiens 
2025-08-23 | E-MTAB-15436 | biostudies-arrayexpress
ProteomicsProteomics of muscle chronological ageing in post-menopausal women
Background Muscle ageing contributes to both loss of functional autonomy and increased morbidity. Muscle atrophy accelerates after 50 years of age, but the mechanisms involved are complex and likely result from the alteration of a variety of interrelated functions. In order to better understand the ...
ORGANISM(S): Homo sapiens (Human) 
2015-02-19 | PXD001527 | Pride
Human Sarcopenia Skeletal muscle Proteomics Ageing Biomarkers 
UnknownRegularized regression outperforms trees for predicting cognitive function in the Health and Retirement Study.
Not available
S-EPMC12652623 | biostudies-literature
UnknownConcomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression.
Not available
S-EPMC8664295 | biostudies-literature
UnknownAssociations Between Infant Screen Use, Electroencephalography Markers, and Cognitive Outcomes.
Not available
S-EPMC9887532 | biostudies-literature
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