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TranscriptomicsGene expression and muscle fiber function in a porcine ICU model
Background: Skeletal muscle wasting and impaired muscle function in response to mechanical ventilation and immobilization in intensive care unit (ICU) patients are clinically challenging partly due to (i) the poorly understood intricate cellular and molecular networks; and (ii) the unavailability of...
ORGANISM(S): Sus scrofa 
2009-08-31 | E-GEOD-16348 | biostudies-arrayexpress
TranscriptomicsDifferential Gene Expression in HDAC7-Deficient and Transgenic Thymocytes
Title of Publication: Histone Deacetylase 7 Regulates Cell Survival and TCR Signaling in CD4/CD8 Double-Positive Thymocytes Abstract of publicaton: CD4/CD8 double-positive (DP) thymocytes express the transcriptional repressor Histone Deacetylase 7 (HDAC7), a class IIa HDAC that is exported from the ...
ORGANISM(S): Mus musculus 
2011-04-06 | E-GEOD-26488 | biostudies-arrayexpress
TranscriptomicsThe Stockholm Atherosclerosis Gene Expression (STAGE) study: Global Gene Expression data from coronary and carotid artery disease patients
Tissue samples have been isolated during corornary artery by-pass grafting (CABG)surgery from the atheroscelrotic arterial wall (AAW, aortic root puncture for proxmal ligation of by-pass vessel), non-atherosclertoci arterial wall (NAAW, distal part of mammary artery used a graft for LAD), liver, sk...
ORGANISM(S): Homo sapiens 
2012-08-21 | E-GEOD-40231 | biostudies-arrayexpress
UnknownOnline-Based and Technology-Assisted Psychiatric Education for Trainees: Scoping Review.
Not available
S-EPMC12041828 | biostudies-literature
TranscriptomicsPDK1 Signaling Towards PLK1-Myc Activation Confers Oncogenic Transformation and Tumor Initiating Cell Activation and Resistance to mTOR-targeted Therapy.
Although 3-Phosphoinositide-dependent protein kinase-1 (PDK1) has been predominately linked to PI3K-AKT pathway, it may also evoke additional signaling outputs to promote tumorigenesis. Here we report that PDK1 directly induces phosphorylation of Polo-like kinase 1 (PLK1), which in turn induces Myc ...
ORGANISM(S): Homo sapiens 
2013-07-31 | E-GEOD-30669 | biostudies-arrayexpress
UnknownThe impact of generative AI on health professional education: A systematic review in the context of student learning.
Not available
S-EPMC12686775 | biostudies-literature
TranscriptomicsBulk RNA-seq of immortalized N/TERT keratinocytes stimulated with IFNγ
Inflammasomes are multicomplex proteins which drive pro-inflammatory cytokine responses and pyroptosis in innate immunity. Of which, the NLRP3 inflammasome is the most extensively studied, especially in myeloid immune cells such as macrophages. Conversely, the regulation of NLRP3 in non-immune cell ...
ORGANISM(S): Homo sapiens 
2025-10-30 | E-MTAB-15754 | biostudies-arrayexpress
UnknownSystematic scoping review on moral distress among physicians
Not available
S-EPMC9442489 | biostudies-literature
TranscriptomicsmiR-21 OVA Lung
Lungs from miR-21+/+ and miR-21-/- mice sensitized with OVA/Alum and challenged with either saline or OVA.
ORGANISM(S): Mus musculus 
2011-08-25 | E-MEXP-3119 | biostudies-arrayexpress
GenomicsGenetic Variation Determines PPARγ Function and Antidiabetic Drug Response In Vivo [ChIP-seq]
SNPs affecting disease risk often reside in non-coding genomic regions. Here we show that SNPs are highly enriched at mouse strain-selective adipose tissue binding sites for PPARγ, a nuclear receptor for antidiabetic drugs. Many such SNPs alter binding motifs for PPARγ or cooperating factors, and fu...
ORGANISM(S): Homo sapiens 
2015-07-02 | E-GEOD-64458 | biostudies-arrayexpress
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