Sort   by:  
 Page size 
UnknownProteomic and genomic studies of non-alcoholic fatty liver disease--clues in the pathogenesis.
Not available
S-EPMC4093687 | biostudies-literature
TranscriptomicsA high-resolution single-cell multiomic atlas of the human fetal lung - scRNA / GEX / VDJ
We obtained human embryonic and fetal lungs from 5-22 pcw for scRNAseq and scATACseq analysis. To focus on epithelial differentiation and region specialization, we deeply sampled 15, 18, 20 and 22 pcw lungs and separated proximal and distal regions while leaving lungs at 5, 6, 9 and 11 pcw intact. T...
ORGANISM(S): Homo sapiens 
2022-01-27 | E-MTAB-11278 | biostudies-arrayexpress
UnknownStudy protocol for the safety and efficacy of probiotic therapy on days alive and out of hospital in adult ICU patients: the multicentre, randomised, placebo-controlled Restoration Of gut microflora in Critical Illness Trial (ROCIT).
Not available
S-EPMC7311035 | biostudies-literature
UnknownConformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex.
Not available
S-EPMC3887373 | biostudies-literature
TranscriptomicsTranscription profiling of uteruses from Alpk:APfCD-1 mice treated with arachis oil (AO) vehicle, 17beta-estradiol (E2), diethylstilbestrol (DES), or genistein (GEN) to study the effects of E2, GEN, and DES on gene transcription.
Three independent replicates of 4 groups of immature (19/20 days of age) Alpk:APfCD-1 mice were treated with arachis oil (AO) vehicle, 2.5ug/kg 17beta-estradiol (E2), 2ug/kg diethylstilbestrol (DES), or 50mg/kg genistein (GEN), via 3 daily subcutaneous injection, and sacrificed 72hr after initial do...
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-1839 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of uteruses from immature Alpk:APfCD-1 mice treated with arachis oil vehicle (AO), 17beta-estradiol (E2), or genistein (GEN) to study the effects of E2 and GEN on gene expression.
Immature (19/20 days of age) Alpk:APfCD-1 mice were treated with arachis oil (AO) vehicle, 0.4mg/kg 17beta-estradiol (E2), or 250mg/kg genistein (GEN), via a single subcutaneous injection, and sacrificed at 1hr, 2hr, 4hr, 8hr, 24hr, 48hr, 72hr post dose.
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-1819 | biostudies-arrayexpress
UnknownGenetic background modifies vulnerability to glaucoma-related phenotypes in Lmx1b mutant mice.
Not available
S-EPMC7903917 | biostudies-literature
ProteomicsOncogenic PKA signaling stabilizes MYC oncoproteins via an aurora kinase A-dependent mechanism
Genetic alterations that activate protein kinase A (PKA) signaling are found across many tumor types, but their downstream oncogenic mechanisms are poorly understood. We used global phosphoproteomics and kinome activity profiling to map the conserved signaling outputs driven by diverse genetic chang...
ORGANISM(S): Homo sapiens (Human) 
2023-02-09 | PXD025508 | Pride
Aurka Fibrolamellar carcinoma Pim2 Pka Myc Liver cancer 
TranscriptomicsAcquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells
Our data show that Wnt and FGF signalling, and the downstream transcription factors NKX2.1 and TFAP2C, promote human alveolar or airway fate respectively. Moreover, we have functionally validated cell-cell interactions in human lung alveolar patterning. We show that Wnt signalling from differentiati...
ORGANISM(S): Homo sapiens 
2022-02-28 | E-MTAB-11435 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of uteri from mice treated with 17beta-estradiol for different durations to study the molecular mechanism for estrogen induced uterine growth.
Immature (19/20 days of age) Alpk:APfCD-1 mice were treated with arachis oil (AO) vehicle or 0.4mg/kg 17beta-estradiol (E2), via a single subcutaneous injection, and sacrificed at 1hr, 2hr, 4hr, 8hr, 24hr, 48hr, 72hr post dose.
ORGANISM(S): Mus musculus 
2007-09-22 | E-GEOD-2195 | biostudies-arrayexpress
Sort   by:  
 Page size