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ProteomicsABCB5+ limbal epithelial stem cells inhibit developmental, but promote inflammatory (lymph)angiogenesis while preventing corneal inflammation
ABCB5 is marker for Limbal epithilal stem cells. A comparison between ABCB5+ versus ABCB5- cultured human limbal epithelial cells was carried out to evaluate the properties of the limbal stem cell ABCB5+ with a special focus on their role in inflammation and angiogenesis.
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD041004 | Pride
(lymph)angiogenesis Cornea Abcb5 Limbal epithelial stem cells 
GenomicsscRNAsequencing of in vitro expanded limbal stem cells of aniridia donors
Identifying potential heterogeneity and expression differences within Aniridia limbal stem cells.
EGAS00001007397 | EGA
TranscriptomicsTranscription profiling of mouse limbal and corneal epithelial basal cells to characterize different gene expression patterns in the two cell types
Limbal vs. corneal epithelial basal cell gene expression patterns were identified and compared. Experiment Overall Design: 8 limbal and 8 corneal epithelial basal cells samples from 8 mice were dissected and mRNAs were isolated and amplified for microarray analysis
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-4098 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human conjunctival epithelial side population cells
Side population (SP) cells isolated from limbal and conjunctival epithelia derive from cells that are slow cycling in vivo, a known feature of tissue stem cells. The purpose of this study was to define the molecular signature of the conjunctival side population cells by global differential gene expr...
ORGANISM(S): Homo sapiens 
2009-11-11 | E-GEOD-12631 | biostudies-arrayexpress
TranscriptomicsLimbal and Central Corneal Epithelia
Limbal and central regoins of the rat cornea epithelium were used to constract 2 SAGE libraries, in order to identify candidate genes to distinguish stem cell from differentiated central cornea epithelium cells. Keywords: gene expression SAGE-based, count cornea epithelium was scraped from central ...
ORGANISM(S): Rattus norvegicus 
2006-05-15 | E-GEOD-4121 | biostudies-arrayexpress
TranscriptomicsCorneal Gene Expression Analysis
Transplantation of amniotic membrane-expanded limbal epithelium (AMLE) in place of donor tissue grafts results in significantly improved outcomes for patients suffering from severe limbal stem cell deficiency; however the reasons for such superior results are unclear. The purpose of this study was t...
ORGANISM(S): Homo sapiens 
2014-10-02 | E-GEOD-56421 | biostudies-arrayexpress
GenomicsRNA-seq of WNT16-treated and Wild Type Human Limbal Epithelial Stem Cells
RNA-seq of WNT16-treated and Wild Type Human Limbal Epithelial Stem Cells
PRJNA749250 | ENA
UnknownComparative proteomics reveals human pluripotent stem cell-derived limbal epithelial stem cells are similar to native ocular surface epithelial cells.
Not available
S-EPMC4589773 | biostudies-literature
GenomicsSingle-cell analysis of limbal niche heterogeneity and crosstalk with corneal epithelial stem/progenitor cells
Single-cell analysis of limbal niche heterogeneity and crosstalk with corneal epithelial stem/progenitor cells
PRJNA661449 | ENA
UnknownSpatial distribution of niche and stem cells in ex vivo human limbal cultures.
Not available
S-EPMC4214849 | biostudies-literature
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