Abstract

Background

The gut microbiota is a key regulator of host lipid metabolism. In indigenous pigs, variation in growth performance and intramuscular fat (IMF) deposition has been linked to microbiota-host interactions, yet the specific taxa and metabolites that govern host lipid ...

Introduction: The gut microbiota and its metabolites are implicated in atherosclerosis, but the specific effector molecules and their pathophysiological significance remain unclear.

Objectives: This study aimed to identify key atheroprotective microbial metabolites and to elucidate the mech...

Upon reaching an OD600 of 0.3, L.

reuteri cultures were treated with 100 µM TCA, HCA, or

TCDCA. For BSHs inhibition assays, additional wells were treated with 100 µM

HCA + GR7. Both negative control and MRS medium control groups were included.

Cultures were terminated at 7...