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Previous studies have demonstrated that the c-Myc transcription factor regulates and cooperates with oncogenic miRNAs to accelerate tumorigenesis. Much recent work has shown that Myc plays an important role in stem cell pluripotency. These findings have prompted us to determine whether Myc regulates...
ORGANISM(S): Mus musculus 
The RUNX genes encode for transcription factors involved in development and human disease. RUNX1 and RUNX3 are frequently associated with leukemias, yet the basis for their involvement in leukemogenesis is not fully understood. Here we show that Runx1;Runx3 double knockout (DKO) mice exhibited letha...
ORGANISM(S): Mus musculus 
We used tobramycin-affinity RNA-pulldown assays coupled with mass spectrometry to identify CK1α 5'-UTR-binding proteins.
ORGANISM(S): Homo sapiens (Human) 
2022-10-01 | PXD027124 | Pride
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