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ProteomicsThe Influences of ApoE Isoforms on Endothelial Adherens Junctions and Actin Cytoskeleton Responding to mCRP
Monomeric C-reactive protein (mCRP) plays a role in cerebrovascular damage mediated by apolipoprotein E4 (ApoE4) in Alzheimer's disease (AD) pathogenesis. Using proteomic profilings, we found altered cytoskeleton proteins in the microvasculature of AD brains, including increased levels of hyperphosp...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-05-06 | PXD051529 | Pride
Apolipoprotein e (apoe)  monomeric c-reactive protein (mcrp)  lim domain and actin binding 1 (lima1)  cd31 and pcd31  cerebrovascular  endothelia  f-actin  alzheimer’s disease (ad) 
ProteomicsGlycolytic enzyme aldolase A is necessary for reelin mediated neurite growth and arborization
Reelin is a large, secreted glycoprotein that is best known as an essential molecule directing neocortical neuronal migration, but reelin serves an important functional role in regulating neurite outgrowth and arborization as well. Canonically, reelin signals through the lipoprotein receptors apolip...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD046667 | Pride
Lc-ms  proteomics  aldolase a  reelin  neurite growth 
UnknownLong noncoding RNA TINCR facilitates hepatocellular carcinoma progression and dampens chemosensitivity to oxaliplatin by regulating the miR-195-3p/ST6GAL1/NF-κB pathway.
Not available
S-EPMC8722212 | biostudies-literature
TranscriptomicsGene expression profiling of rice embryogenic calli after Agrobacterium infection
Agrobacterium tumefaciens-mediated genetic transformation has been routinely used in rice for more than a decade. However, the transformation efficiency of the indica rice variety is still unsatisfactory and much lower than that of japonica cultivars. Further improvement on the transformation effici...
ORGANISM(S): Oryza sativa Japonica Group 
2012-01-01 | E-GEOD-32426 | biostudies-arrayexpress
TranscriptomicsSingle-nucleus RNA-seq of FACS-enriched Glp1r-Sun1-sfGFP nuclei from mouse hypothalamus, dorsal vagal complex, and nodose ganglion
Glucagon-like peptide-1 receptor (GLP1R) agonists such as semaglutide reduce food intake and body weight, and Glp1r-expressing neurons in the hypothalamus and hindbrain mediate these effects. To profile these cells directly, Glp1r-Cre mice were crossed to the Gt(ROSA)26Sor-CAG-Sun1-sfGFP reporter, w...
ORGANISM(S): Mus musculus 
2026-09-14 | E-MTAB-17566 | biostudies-arrayexpress
MetabolomicsCell type-specific proteomics uncovers a RAF15-SnRK2.6/OST1 kinase cascade in guard cells

Multicellular organisms such as plants contain various cell types with specialized functions. Analyzing the characteristics of each cell type reveals specific cell functions and enhances our understanding of organization and function at the organismal level. Guard cells (GCs) are specialized epid...

2024-09-03 | MTBLS3997 | MetaboLights
UnknownThe features of male breast cancer in China: A real-world study.
Not available
S-EPMC11259957 | biostudies-literature
UnknownContinuous positive airway pressure (CPAP) vs noninvasive positive pressure ventilation (NIPPV) vs noninvasive high frequency oscillation ventilation (NHFOV) as post-extubation support in preterm neonates: protocol for an assessor-blinded, multicenter, randomized controlled trial.
Not available
S-EPMC6659219 | biostudies-literature
UnknownComparison of the Oral Calcimimetics Evocalcet and Cinacalcet in East Asian Patients on Hemodialysis with Secondary Hyperparathyroidism.
Not available
S-EPMC10658267 | biostudies-literature
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