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ProteomicsJMJD2 regulates enhancer-promoter interactions via biocondensate formation
Enhancer-promoter (E-P) interactions regulate transcription for cell fate determination. However, the regulatory mechanisms of E-P interactions remain elusive. Here, a chromatin interaction-based proteomics approach, LoopID, was developed to profile the proteins at certain E-P anchors, which were te...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-16 | PXD069064 | Pride
Enhancer-promoter interactions Proximity ligation Loopid Biocondensates Proteome 
UnknownA Novel Banana Mutant "RF 1" (Musa spp. ABB, Pisang Awak Subgroup) for Improved Agronomic Traits and Enhanced Cold Tolerance and Disease Resistance.
Not available
S-EPMC8496975 | biostudies-literature
UnknownroX1 and roX2 lncRNAs promote heterochromatinization in intestinal stem cells and impair longevity
Not available
S-SCDT-10_1038-S44319-026-00791-8 | biostudies-other
ProteomicsLabel-free serum proteome in the rabbit CAS provocation model
A rabbit CAS provocation model was established to screen potential diagnostic biomarkers using quantitative serum proteomics
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-29 | PXD036383 |
ProteomicsMS analysis of human TFEB posttranslational modification
Mass spectrometry analysis of TFEB acetylation, phosphorylation, and ubiquitination without or with TSA treatment
ORGANISM(S): Homo Sapiens 
2022-08-08 | PXD035879 |
ProteomicsSelenium Supplementation Elevated SELENBP1 to Inhibit Fibroblast Activation in Pulmonary Arterial Hypertension
Prophylactic selenium supplementation could effectively improve hemodynamics and pulmonary vascular remodeling in monocrotaline-induced pulmonary hypertension rat models. We scanned the selenium-related proteins through proteomic profiles on pulmonary artery branches of monocrataline rats versus con...
ORGANISM(S): Rattus Norvegicus 
2024-09-22 | PXD056117 |
ProteomicsAntipsychotic cardiotoxicity and its mechanisms
Antipsychotic (AP) drugs are common agents for treating mental disorders such as schizophrenia, bipolar disorder, and major depressive disorder. Overall AP prescription increased 3.8-fold, while second-generation AP (SGA) prescriptions increased 18.1-fold during a 16-year follow-up. The increased us...
ORGANISM(S): Mus Musculus 
2021-12-22 | PXD030588 |
ProteomicsNuclear polysaccharides maintain H3K9me3-heterochromatin and genomic stability
Polysaccharides are traditionally confined to the cell surface and extracellular space, whereas their nuclear roles remain unclear. Here, we show that N-glycans are present in the nucleus and modify inner nuclear membrane (INM) proteins across multiple cell types. Disruption of INM protein N-glycosy...
ORGANISM(S): Mus Musculus 
2025-12-30 | PXD072505 |
ProteomicsNuclear condensation of CDYL links histone crotonylation and cystogenesis in autosomal dominant polycystic kidney disease
We identify the Kcr sites on histones that are targeted by CDYL in ADPKD cells (WT9-12 cells). We chose to knock out CDYL in WT 9-12 cells (CDYL KO) through CRISPR/Cas9-mediated gene editing to increase the overall levels of histone Kcr. We quantified Kcr modifications on different histone residues ...
ORGANISM(S): Homo Sapiens 
2022-01-17 | PXD031029 |
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