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MetabolomicsUntargeted Metabolomics of the enthesis interstitial fluid of wild-type and Nlrp3-/- mice with sham operation and injury post 7 days
In order to investigate the effect of the NLRP3 inflammasome on the regeneration of enthesis, we established an enthesis injury and repair model in wild-type and NLRP3-/- mice. The interstitial fluid of enthesis was extracted, and untargeted metabolomics was conducted to discover differential metabo...
2025-07-08 | MTBLS12150 | MetaboLights
MetabolomicsUntargeted metabolites of supernatant of wild-type and Nlrp3-/- bone marrow-derived macrophages with or without LPS and ATP costimulation
Untargeted metabolites of supernatant of wild-type and Nlrp3-/- bone marrow-derived macrophages without stimulation or with 4 hours of LPS preconditioning and subsequently 30 min of ATP stimulation.
2025-07-08 | MTBLS12152 | MetaboLights
ProteomicsGPX4 immunoprecipitation in Huh7 cells
Huh7 cells with expression of Flag-GPX4 were treated with IGF1. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
ORGANISM(S): Human 
2023-02-22 | MSV000091343 | MassIVE
ProteomicsProteomic analysis of brain tissue from ducks with meningitis caused by Riemerella anatipestifer infection
To investigate the key molecules or proteins involved in Riemerella anatipestifer’s penetration of the blood-brain barrier and the subsequent development of duck meningitis, a duck meningitis model was established and characterized. Duckling brain tissues were collected and analyzed using 4D label-f...
ORGANISM(S): Anas Nesiotis 
2024-06-07 | PXD052981 |
ProteomicsAn exosome-based one-step high-throughput microfluidic platform for epithelial ovarian cancer diagnosis
Exosomes, reflecting the live cellular state, hold promise for non-invasive disease detection. However, the significance of exosome cargos has been underestimated, particularly in the clinic, mainly due to the scarcity of exosome. Here, we present a "one-step" high-throughput microfluidic platform i...
ORGANISM(S): Homo Sapiens 
2024-07-04 | PXD053690 |
ProteomicsER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ER-associated degradation ligase HRD1 links ER stress to DNA damage repair by modulating the activity of DNA-PKcs
ORGANISM(S): Homo Sapiens 
2024-08-20 | PXD055020 |
ProteomicsLISS enables immune evasion of colorectal cancers irrespective of MSI status
LISS enables immune evasion of colorectal cancers irrespective of MSI status
ORGANISM(S): Homo Sapiens 
2026-05-25 | PXD078805 |
ProteomicsTargeting ubiquitin-independent proteasome with small molecule increases susceptibility in pan-KRAS mutant cancers
Despite advances in the development of direct KRAS inhibitors, KRAS-mutant cancers continue to exhibit resistance to the currently available therapies. Here, we identified REGγ as a mutant KRAS-associated factor that enhances REGγ transcription through the KRAS intermediate NRF2, suggesting that the...
ORGANISM(S): Homo Sapiens 
2025-01-01 | PXD059364 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
UnknownLong-term safety of canakinumab in patients with systemic juvenile idiopathic arthritis: 5-year results from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) registry.
Not available
S-EPMC12538899 | biostudies-literature
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