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TranscriptomicsAnalysis of cardiac gene expression in response to isoproterenol-induced heart failure (part 1)
Myoglobin knockout mice (myo-/-) adapt to the loss of myoglobin by the activation of a variety of compensatory mechanisms on the structural and functional level. In order to analyze to what extent myo-/- mice would tolerate cardiac stress we used the model of chronic isoproterenol application to ind...
ORGANISM(S): Mus musculus 
2010-05-31 | E-GEOD-16243 | biostudies-arrayexpress
TranscriptomicsAnalysis of cardiac gene expression in response to isoproterenol-induced heart failure (part 2)
Myoglobin knockout mice (myo-/-) adapt to the loss of myoglobin by the activation of a variety of compensatory mechanisms on the structural and functional level. In order to analyze to what extent myo-/- mice would tolerate cardiac stress we used the model of chronic isoproterenol application to ind...
ORGANISM(S): Mus musculus 
2010-05-31 | E-GEOD-16246 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of transgenic mice (tTA/IkappaBalpha-AA) treated with doxycycline (DOX), which represses expression of the transgenic IkappaBalpha
double transgenic mice (tTA/IkappaBalpha-AA) were treated with doxycycline (DOX), which represses expression of the transgenic IkappaBalpha. Double transgenic mice without Dox-treatment overexpress the transdominant IkappaBalpha, which represses NFkappaB activation.
ORGANISM(S): Mus musculus 
2006-05-10 | E-MEXP-358 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood monocytes after constitutive adhesion to naive human umbilical vein endothelial cells (HUVEC) to investigate changes in gene expression patterns
Investigation of the alterations in the gene expression pattern of peripheral blood monocytes after constitutive adhesion to naive human umbilical vein endothelial cells
ORGANISM(S): Homo sapiens 
2007-03-10 | E-MEXP-854 | biostudies-arrayexpress
TranscriptomicsIGF1-receptor signalling attenuates the age-related decline of diastolic cardiac function
Insulin-like growth factor (IGF1R) signalling has been implicated to play an important role in regulation of cardiac growth, hypertrophy and contractile function, and has been linked to the development of age related congestive heart failure. Here we address the question to what extent cardiomyocyte...
ORGANISM(S): Mus musculus 
2012-07-31 | E-GEOD-32936 | biostudies-arrayexpress
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